BACKGROUND Alcoholic liver disease is associated with increased hepatic expression of monocyte chemoattractant protein 1 (MCP-1) and macrophage inflammatory protein 1alpha (MIP-1alpha). AIMS To determine whether concentrations of chemokines in the peripheral circulation reflect disease activity, and whether chemokine secretion is restricted to the liver or is part of a systemic inflammatory r...

We compared the relationships of alcoholic fatty liver and nonalcoholic fatty liver with hypertension, diabetes mellitus, and dyslipidemia. Using a nationwide Japanese survey, we collected data on subjects with biopsy-proven alcoholic fatty liver or nonalcoholic fatty liver. Multiple logistic regression analysis was performed to determine whether alcoholic fatty liver and nonalcoholic fatty liv...

The objective of the research was to study the features of the indicators of the humoral component of the immune system depending on the body mass index in patients with non-alcoholic hepatic steatosis, non-alcoholic steatohepatitis, concomitant obesity and biliary tract pathology. Material and methods. 200 patients with non-alcoholic fatty liver disease, concomitant obesity and biliary tract p...

Chronic alcohol consumption is associated with increased incidence of variety of illnesses including cirrhosis. Studies have shown that ethanol consumption may result in increased oxidative stress with increased formation of lipid peroxides and free radicals. However, very few reports are available on their involvement in the toxicity of alcoholic cirrhosis. The present study was undertaken in ...

Abstract Background COVID-19 vaccination of the population has a great importance, especially in oncological patients. The high incidence vaccine-associated hypermetabolic lymphadenopathy (VAHL) makes difficulty diagnosis PET-CT They should be vaccinated side opposite to expected malignant LNs avoid unnecessary biopsy and change therapy. aim this study was assess role detection VAHL after 2nd d...

Alcohol and dietary intake were determined in alcoholic patients with chronic pancreatitis and alcoholic liver disease. Patients with chronic pancreatitis, alcoholic hepatitis, and cirrhosis ingested approximately 50% of their calories as alcohol, and all had low mean intakes of protein, carbohydrate, and fat as compared with control subjects. Patients with severe alcoholic hepatitis had the lo...

BACKGROUND Hepatic stellate cell (HSC) has been suggested to play a role in fibrogenesis in alcoholic liver disease. We evaluate the correlation with fibrogenesis and ultrastructure of hepatic stellate cells in alcoholic fatty liver. METHODS We studied 6 patients with alcoholic fatty liver and 5 non-alcoholic fatty liver. The numbers of fat droplets in hepatic stellate cell was determined by ...

A Mallory body (alcoholic hyaline) antigen (JMB2) which is also present in intermediate filaments of epithelial origin was demonstrated immunohistochemically in renal glomeruli of three out of eleven patients with alcoholic liver damage. In two of these patients, both of whom had alcoholic cirrhosis with Mallory bodies, it was associated with mesangial deposits of IgA and C3. JMB2 was not found...