background: world health organization report in 2014 indicates a considerable range of alcohol consumption across the world which had a growing trend during last 5 years. a study on 5,231 students in 57 universities has shown that alcohol consumption became more common than other drugs, and alcohol is in the first rank for repeated usage. in another study in 2010, the prevalence of alcohol use ...

The DSM-V Committee plans to abolish the distinction between Alcohol Abuse and Alcohol Dependence (dsm5.org). The author presents a case report as a proof of concept that this distinction should be retained. The author has asserted that Alcohol Abuse is a purely psychological addiction, while Alcohol Dependence involves capture of the ventral tegmental dopaminergic SEEKING system (Johnson, 2003...

A field study was designed to determine if traffic offenders were characterised by substance-related and addictive disorders behavioural addictions, examine their prevalence in this population. total of 268 regular drivers (weekly or daily use) participated the study; 132 incarcerated 136 with no criminal background. Subsamples matched age, sex, time elapsed since driving test. Participants res...

Alcohol use disorders (AUDs) may be associated with several psychological and affective disorders. It is controversial, however, if these symptoms are a cause or rather a consequence of alcohol dependence. There are few data testing simultaneously psychosocial and affective disorders before and after a period of alcohol abstinence. The aim of this study was to perform multiple psychometric eval...

alcohol directly affects astroglial cell function, including inflammation-related activity.  and it also affects microglial cell development and function in specific ways that interfere with microglial interactions with the immune system and with neurons. neuroinflammatory processes might be involved in alcohol-induced brain damage. alcohol use, misuse and getting used to it causes different ki...

This article reviews scientific advances in the prevention and treatment of substance-use disorder and related developments in public policy. In the past two decades, research has increasingly supported the view that addiction is a disease of the brain. Although the brain disease model of addiction has yielded effective preventive measures, treatment interventions, and public health policies to...

Alcohol abuse is a major health, economic and social concern in modern societies, but the exact molecular mechanisms underlying ethanol addiction remain elusive. Recent findings show that small non-coding microRNA (miRNA) signaling contributes to complex behavioral disorders including drug addiction. However, the role of miRNAs in ethanol-induced conditioned-place preference (CPP) and voluntary...

Alcohol dependence causes physical, social, and moral harms and currently represents an important public health concern. According to the World Health Organization (WHO), alcoholism is the third leading cause of death worldwide, after tobacco consumption and hypertension. Recent epidemiologic studies have shown a growing trend in alcohol abuse among adolescents, characterized by the consumption...

Onset of alcohol use at an early age increases the risk for later alcohol dependence. We investigated the role of the glucocorticoid receptor (GR) gene (NR3C1) in onset of alcohol use and abuse in 14-year-old adolescents (n=4534). Several NR3C1 polymorphisms were associated with onset of alcohol drinking or drunkenness at this age. Strongest associations were observed in females, with one marke...

consumption and problems among the Irish in London: A preliminary comparison of pub drinkers in London and Dublin, (Author postprint) in Addiction Research & Theory, 12(4), 373-384 , [Accessed: (date) from www.drugsandalcohol.ie] 1 Note: This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Addiction Research & Theory following peer review. The definitive pub...