Nanotechnology is emerging as a rapidly growing field with its wide application in science and technology for manufacturing of new materials at nanoscale level (Albrecht et al., 2006). This technology gained a tremendous impetus due to its capability of reformulating metals into new nanosized particles, with dimension less than 100 nm in size. Due to nanoparticle size, their physio-chemical pro...

Gene therapy can be defined as the transfer of genetic materials to specific cells in order to exert a therapeutic effect. Gene therapy is a promising approach to the treatment of a wide range of diseases by compensating for defective genes or producing beneficial proteins (Zhao et al., 2009; Mansouri et al., 2004). Gene vectors play many important roles in gene therapy. Recently, nonviral vect...

a r t i c l e i n f o Keywords: Biodegradable polymer PHBHHx Kaolin Core–shell nanoparticle Nanocomposite A novel biodegradable nanocomposite was fabricated based on poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) and silane-modified kaolinite/silica core–shell nanoparticles (SMKS), via solution-casting method using chloroform as solvent. Unmodified (ORK) and glycidoxypropyltrimethoxysi...

Purpose: This article describes the preparation and characterization of folate conjugated nanoparticles using poly(lactide-co-glycolide)-poly(ethylene glycol)-folate (PLGA-PEG-FOL) polymer for targeted delivery of anticancer agents. Methods: PLGA-PEG-FOL was synthesized by coupling di-block copolymer (PLGA-PEG-NH2) with folic acid. PLGA-PEG-FOL polymer was characterized by 1H NMR, GPC and FTIR....

Submit Manuscript | http://medcraveonline.com cellular and cellular based mechanisms of resistance and to increase selectivity of drugs [1]. In this way as an example, Wang et al. [2] reported that targeted magnetic nanoparticles containing 5-FU can improve the chemotherapeutic effect of 5-FU against hepatocellular carcinoma. Nanoparticles may be defined as colloidal systems (<1 μm), generally ...

The aim of the investigation was to assess the pharmacokinetic parameters of wheat germ agglutinin (WGA)-grafted nanoparticles of mometasone furoate (MF), after intratracheal instillation in rats. PLGA (50:50) nanoparticles (NPs) loaded with MF were prepared by emulsion-solvent evaporation technique. WGA was conjugated to spherical MF loaded nanoparticles by carbodiimide coupling yielding a lig...

0021-9517/$ see front matter 2010 Elsevier Inc. A doi:10.1016/j.jcat.2010.06.017 * Corresponding author. Fax: +1 510 642 4778. E-mail address: [email protected] (A.T. Bel A novel approach is described for preparing Ga-promoted Pt particles for the dehydrogenation of light alkanes to alkenes. The modifying element, Ga, was introduced by transference from the support, a calcined Mg(Ga)(Al)O...

Hydrogen plays an essential role during the in situ assembly of tailored catalytic materials, and serves as key ingredient in multifarious chemical reactions promoted by these catalysts. Despite intensive debate for several decades, the existence and nature of hydrogen-involved mechanisms - such as hydrogen-spillover, surface migration - have not been unambiguously proven and elucidated up to d...