Enantiomerically pure 2-benzylindane derivatives were prepared using biocatalytic methods and their absolute configuration determined. (1R,2S)-2-Benzylindan-1-ol ((1R,2S)-2) and (S)-2-benzylindan-1-one ((S)-3) were produced by fermenting baker's yeast. Lipase-mediated esterifications and hydrolysis of the corresponding racemic substrates gave rise to the enantiopure compounds (1S,2R)-2-benzylin...

The response of the two most abundant cockchafer species in central Europe, Melolontha hippocastani and M. melolontha, towards phenol, mixtures of phenol with the leaf alcohol (Z)-3-hexen-1-ol and the known cockchafer pheromones, 1,4-benzoquinone (M. hippocastani) and toluquinone (M. melolontha), was investigated in the field. During the swarming period at dusk, phenol attracted males of both s...

Reactive oxygen species (ROS) are signaling molecules that mediate stress response, apoptosis, DNA damage, gene expression and differentiation. We report here that differentiation of oligodendrocytes (OLs), the myelin forming cells in the CNS, is driven by ROS. To dissect the OL differentiation pathway, we used the cell line MO3-13, which display the molecular and cellular features of OL precur...

PURPOSE To determine the active ingredient in tea tree oil (TTO) responsible for its reported killing effect on Demodex mites, the most common ectoparasite found in the human skin extending to the eye. METHODS Using a reported in vitro killing assay to measure the survival time of adult Demodex folliculorum up to 150 minutes, we have screened serial concentrations of 13 of the 15 known ingred...

The contribution of the great poet Alisher Navoi to development, improvement and progress ancient Uzbek literary language is incomparable. Turkish has acquired a high status thanks his works. lexicon used in work thinker, some extent, serves as basis for determining Old language. Historical works author, such “Tarihi Muluki Ajam” Anbiyo va Hukamo”, were selected object research. article analyze...

Henselian elements are roots of polynomials which satisfy the conditions of Hensel’s Lemma. In this paper we prove that for a finite field extension (F |L, v), if F is contained in the absolute inertia field of L, then the valuation ring OF of (F, v) is generated as an OL-algebra by henselian elements. Moreover, we give a list of equivalent conditions under which OF is generated over OL by fini...

Anastrazole and Letrozole are used as endocrine therapy for breast cancer patients. Previous studies suggested a possible association with metabolic and liver adverse effects. Their results are conflicting. Fifty-five 4-week-old female Wistar rats were allocated in 4 groups 1) ovariectomy control (OC), 2) ovariectomy-Anastrazole (OA) 3) ovariectomy -Letrozole (OL), 4) control. Serum glucose, ch...

In this letter, we present a novel receiver for time transfer that achieves picosecond accuracy through a line-of-sight link. The receiver is based on a fully integrated optically locked voltage controlled oscillator (OL-VCO) and is implemented in a commercial CMOS process. The design of optical photodiodes integrated with the OL-VCO is explained in detail. It is demonstrated that in the locked...

A new farnane-type pentacyclic triterpene, farnan-2-one-3 beta-ol (mimusopfarnanol), was isolated from the stem bark of Mimusops elengi L. along with the known triterpenoids, farnan-3-one, olean-18-en-2-one-3-ol and lup-20 (29)-en-3 beta-ol and their structures have been characterized on the basis of spectral data analyses and chemical reactions.