Replication-deficient adenovirus and modified vaccinia virus Ankara (MVA) vectors expressing single pre-erythrocytic or blood-stage Plasmodium falciparum Ags have entered clinical testing using a heterologous prime-boost immunization approach. In this study, we investigated the utility of the same immunization regimen when combining viral vectored vaccines expressing the 42-kDa C terminus of th...

An asymmetric fourth cell division in the sea urchin embryo results in formation of daughter cells, macromeres and micromeres, with distinct sizes and fates. Several lines of functional evidence presented here, including pharmacological interference and dominant negative protein expression, indicate that heterotrimeric G protein Gi and its interaction partner, activator of G-protein signaling (...

BACKGROUND The present study was designed to determine whether Allium ursinum L (ramson) could inhibit the proliferation of human AGS gastric cancer cells. Furthermore, we attempted to determine whether this inhibition could occur by targeting regulatory elements of the cell cycle. METHODS Flow cytometry was used to observe apoptosis and the cell cycle in AGS cell lines treated or not treated...

The ability for the professional APC to cross-present Ag to MHC class I from parenchymal cells is essential for priming as well as tolerance of CD8+ T cells against intracellular Ags. Since cross-presentations of non-cell-associated free Ags are inefficient, the roles of molecular chaperones or heat shock proteins (HSPs) in chaperoning Ags to APCs have been postulated. We herein genetically add...

An attention U-Net was proposed to reconstruct the missing chlorophyll-a concentration (Cchla) data. The is a lightweight full convolution neural network architecture consisting of an enccoder-decoder (i.e., down-sampling and up-sampling). gates (AGs) were integrated into U-Net. Training with AGs could implicitly teach it suppress irrelevant areas highlight salient features in data areas, which...

Anthropogenic land use change (LUC) affects soil quality and the global carbon (C) pool. Such LUC is a potential threat for forest ecosystems because it can alter biome increases emission of greenhouse gasses (GHGs). Here, we investigated changes in CO2 following afforestation reclaimed coal mine agriculture created tropical dry deciduous Jharkhand, India. Soil samples were collected from affor...