UNLABELLED Chimeric antigen receptors (CAR) are recombinant receptors that provide both antigen-binding and T-cell-activating functions. A multitude of CARs has been reported over the past decade, targeting an array of cell surface tumor antigens. Their biologic functions have dramatically changed following the introduction of tripartite receptors comprising a costimulatory domain, termed secon...

The emergence of on-demand transport services is set to change the mobility landscape in urban areas. This study investigates potential scalability an system substitute motorised trips performed by private cars and public Amsterdam, Netherlands. We adopt agent-based simulation framework investigate scenarios where either pooled replace car trips, or both trips. Service performance terms level s...

Coherent anti-Stokes Raman scattering (CARS) of carbon nanostructures, namely, highly oriented pyrolytic graphite, graphene nanoplatelets, graphene oxide, and multiwall carbon nanotubes as well CARS spectra of thymine (Thy) molecules adsorbed on graphene oxide were studied. The spectra of the samples were compared with spontaneous Raman scattering (RS) spectra. The CARS spectra of Thy adsorbed ...

In this paper, we address the question if there is a disruption of individual mobility by self-driving cars ahead. In order to answer this question, we take the user perspective and conduct a longitudinal study of social media data about self-driving cars from Twitter. The study analyzes 601,778 tweets from March 2015 to July 2016. We use supervised machine learning classification to extract re...

PURPOSE The Children's Activity Rating Scale (CARS) is a rating scale that is used in direct observation of physical activity in children. Direct observation is costly and tedious, and accuracy may decrease as the observation period lengthens. Recently, motion sensors have gained acceptance for assessment of physical activity. The purpose of this study was to compare 6 h of activity levels usin...

In recent years, all major automotive companies have launched initiatives towards cars that assist people in making driving decisions. The ultimate goal of all these efforts are cars that can drive themselves. The benefit of such a technology could be enormous. At present, some 42,000 people die every year in traffic accidents in the U.S., mostly because of human error. Self-driving cars could ...

Intense CARS spectra were observed in bromine vapour, which could be attributed to resonances in the molecular as well as atomic species. From accurate measurements of frequency positions and polarization dependencies a vibrational overtone sequence Av=2-12, characteristic for resonance CARS, was identified for Br,. Doublets of rotational lines reveal enhancement by discrete transitions between...

T he major role that computational devices play in cars became dramatically apparent last September, when the Environmental Protection Agency announced the results of its investigation into Volkswagen. The EPA discovered that the German automaker had installed software in some of its diesel-engine cars that controlled a system for reducing the emission of environmentally hostile nitrogen oxides...

Advances in vehicle design and fuel quality mean cars can be made cleaner and more efficient. Lower emissions of carbon monoxide (CO), nitrogen oxides (NOx), sulphur dioxide (SO2), particles (including the fine dust and soot PM10) and hydrocarbons (HCs) also known as volatile organic compounds (VOCs) will lead to better urban air quality and less summertime smog. Lower emissions of carbon dioxi...