In consultations with older women, doctors should ask about sexual problems. A holistic approach is needed to examine the many different factors that can affect sexuality. Hormonal changes associated with ageing have an impact on women's sexuality. Doctors need to have a clear idea of the place of hormonal treatment for different sexual problems. Physical changes associated with ageing, includi...

Cyclic adenosine monophosphate (cAMP) plays an important role in many biological processes as a second messenger, and cAMP treatment has been reported to extend the lifespan of wild-type Drosophila melanogaster. Our study showed that exogenous cAMP improved ageing-related phenotypes by increasing the protein level of Sirtuins, which prevented metabolic disorders to mimic the effect of calorie r...

background: increased life expectancy and the growing phenomenon of aging can lead to increased burden of chronic diseases (cds) which adversely affects the overall health of elderly, their sexuality in particular. sexual life of aged population is overlooked in many of the societies. in the present narrative review, we aim to assess the impact of cds on sexual function of elderly people. mater...

introduction: motor skills play an important role during life span, and older adults need to learn or relearn these skills. the purpose of this study was to investigate how aging affects induction of improved movement performance by motor training. methods: serial reaction time test (srtt) was used to assess movement performance during 8 blocks of motor training. participants were tested in two...

Microalloyed cast steels are a group of microalloyed steels in which reliable mechanical properties could be achieved by heat treatment. In this work, the heat treatment processes were carried out on the cast specimens as the step samples by different thicknesses and Zr content. The results show that after homogenization, variations in thickness have no effect on the hardness. Also, after hea...

Coenzyme Q(10) (CoQ(10) ) is a well-known antioxidant and has been used in many skincare products for anti-ageing purpose. However, the molecular mechanisms of CoQ(10) function in skin cells are not fully understood. In this paper, we compared the effects of CoQ(10) on primary human dermal fibroblasts from three individuals, including adult. We demonstrated that CoQ(10) treatment promoted p...

The effect of long period stacking ordered (LPSO) phase and γ' precipitates on the ageing behavior and mechanical properties of the extruded Mg-8.2Gd-3.8Y-1.0Zn-0.4Zr (wt.%) alloy was investigated. The results show that more β' phases precipitate during ageing treatment in the LPSO phase containing alloy so that the LPSO phase containing alloy exhibits a higher age-hardening response than the γ...

The critical node (CN), which is the transition from the plateau phase to the rapid decreasing phase of seed ageing, is extremely important for seed conservation. Although numerous studies have investigated the oxidative stress during seed ageing, information on the changes in protein abundance at the CN is limited. In this study, we aimed to investigate the abundance and carbonylation patterns...

The effects of oral administration of a lactococcal strain on physiological changes associated with ageing were investigated using senescence-accelerated mice (SAM). SAM develop normally, but then show an early onset and irreversible advancement of senescence. SAMP6 is a SAM strain that develops osteoporosis with ageing. Oral administration of heat-killed Lactococcus lactis subsp. cremoris H61 ...