Background: Vancomycin has been widely used in the treatment of infections caused by Methicillin-Resistant Staphylococcus Aureus (MRSA). The emergence of VancomycinIntermediate and -Resistant Staphylococcus Aureus (VISA and VRSA, respectively) in various parts of the world has been of great concern in clinical settings. Objective: This study was performed to evaluate the possible presence of VI...

Lack of correlation between quantitative minimal inhibitory concentration (MIC) determinations and disk diffusion susceptibility tests in our laboratory prompted a study to reevaluate the use of the disk diffusion test for sulfonamide susceptibility testing of Neisseria meningitidis. One hundred and sixty-three recent clinical isolates of N. meningitidis were examined for sulfonamide susceptibi...

male and female leaves and fruits of eleven different taxons of iranian conifers (cupressus sempervirens var. horizontalis, c. sempervirens var. sempervirens, c. sempervirens cv. cereifeormis, juniperus communis subsp. hemisphaerica, j. excelsa subsp. excelsa, j. excelsa subsp. polycarpos, j. foetidissima, j. oblonga, j. sabina, platycladus orientalis and taxus baccata) were collected from diff...

BACKGROUND Antimicrobial-resistant Neisseria gonorrhoeae is a major public health threat. Current CDC treatment guidelines for uncomplicated gonorrhoea recommend only ceftriaxone plus either azithromycin or doxycycline. Additional treatment options are needed. METHODS We used antibiotic gradient synergy testing (the Etest) to evaluate antimicrobial combinations that included a third-generatio...

The in vitro activity of ciprofloxacin against 30 Bacteroides fragilis group, 30 Clostridium, and 30 Peptococcaceae strains was determined by the agar dilution method in two different culture media at three pH and in three inoculum densities. In Wilkins-Chalgren agar the MICs for 90% of the strains were 0.12 micrograms/ml for B. fragilis, 0.5 micrograms/ml for Clostridium spp., and 2 micrograms...

The minimal inhibitory concentrations of cefmenoxime, cefotaxime, cefoxitin, ceftriaxone, chloramphenicol, clindamycin, and moxalactam were determined by agar dilution for 202 clinical isolates of anaerobic bacteria. Cefoxitin and moxalactam were the most active among the cephalosporin-like compounds.

By drug dilution tests in agar, it has been shown that each of 27 strains of Nocardia asteroides was inhibited by 1 mug or less of amikacin per ml of medium.

Susceptibility of 64 clinical isolates of Neisseria gonorrhoeae to metronidazole was determined by the agar dilution technique using Mueller-Hinton and chocolate agar media. All isolates were resistant to metronidazole at 12.5 mug/ml in either medium. This lack of activity of metronidazole against N. gonorrhoeae would suggest that the ability to recover N. gonorrhoeae in patients being treated ...

When tested by agar dilution on Mueller-Hinton agar supplemented with 5% horse blood, the ketolides HMR 3004 and HMR 3647 were slightly more active (MIC at which 90% of the isolates were inhibited [MIC90], 0.03 microg/ml) against Bordetella pertussis than azithromycin, clarithromycin, erythromycin A, and roxithromycin. Azithromycin (MIC90, 0.06 microg/ml) was the most active compound against B....

Using 21 antimicrobial agents, agar dilution susceptibility tests were carried out against 190 strains of Yersinia enterocolitica. Isolates from human, environmental, and animal sources had essentially equal susceptibility patterns.