Pseudomonas aeruginosa is one of the most common causes of keratitis. The current study was done to evaluate the therapeutic effects of antibacterial combinations with Silver nanoparticles (Ag-NPs) and Ciprofloxacin in experimental Pseudomonas keratitis. Sixty four New Zealand rabbits were prepared. All rabbits were randomly categorized into eight groups (each group containing eight rabbits): C...

Objective(s):   Metal nanoparticles (NPs) offer a wide variety of potential applications in pharmaceutical sciences due to the unique advances in nanotechnology research. In this work, bimetal Ag-Au alloy NPs were prepared and their combinations with other antibiotics were tested against Staphylococcus aureus.   Materials and Methods: Firstly, Ag-Au alloy NPs with Au/Ag molar ratio of 1:1 was f...

The reactions of human and bovine retinal S-antigen (S-ag) with polyclonal rabbit antibodies were compared in ELISA, immunoblotting and inhibition ELISA. Titrations in ELISA with plastic-adsorbed S-ags revealed that the great majority (70-100%) of human S-ag epitopes and anti-human S-ag antibodies were cross-reactive. In contrast, the cross-reactivity of bovine S-ag (25%) and anti-bovine S-ag a...

TWO DISTINCT VIRAL ANTIGENS ARE ASSOCIATED WITH THE HEPATITIS B VIRUS: the hepatitis B surface antigen (HB(s)Ag, Australia antigen) and the hepatitis B core antigen (HB(c)Ag). HB(s)Ag, purified from the serum of asymptomatic human HB(s)Ag carriers, and HB(c)Ag, purified from the liver of a chimpanzee acutely infected with hepatitis B virus, were examined by serological and immune electron micro...

The processing and presentation of Ag by Ag-specific B cells is highly efficient due to the dual function of the B cell Ag receptor (BCR) in both signaling for enhanced processing and endocytosing bound Ag. The BCR for IgG (FcgammaRIIB1) is a potent negative coreceptor of the BCR that blocks Ag-induced B cell proliferation. Here we investigate the influence of the FcgammaRIIB1 on BCR-mediated A...

We report the systematic appearance of a plasmon-like optical absorption feature in silver clusters protected with 2-phenylethanethiol (PET), 4-flurothiophenol (4-FTP) and (4-(t-butyl)benzenethiol (BBS) as a function of cluster size. A wide range of clusters, namely, Ag₄₄(4-FTP)₃₀, Ag₅₅(PET)₃₁, ∼Ag₇₅(PET)₄₀, ∼Ag₁₁₄(PET)₄₆, Ag₁₅₂(PET)₆₀, ∼Ag₂₀₂(BBS)₇₀, ∼Ag₄₂₃(PET)₁₀₅, and ∼Ag₅₃₀(PET)₁₀₀ were pre...

Silver deposited titania (Ag/TiO2) nanocomposite thin films were fabricated by the simple sonochemical deposition of Ag on preformed aerosol-assisted chemical vapor deposited TiO2 thin films. The photelectrocatalytic performance of a newly fabricated Ag/TiO2-modified photoelectrode was studied for methanol oxidation under simulated solar AM 1.5G irradiation (100 mW/cm2). The Ag/TiO2-modified ph...

Hepatitis B core antigen (HBc Ag) and hepatitis B surface antigen (HBs Ag) were detected in the liver tissue of a patient with chronic aggressive hepatitis by the immunofluorescent complement technique. The presence of anti-HBc was examined by the same method in 67 human sera previously tested for HBs Ag, anti-HBs and s-GPT levels. HBc Ag was localized mainly in the nucleus and sometimes in the...

Calcium phosphate bone cements (CPCs) with antibacterial properties are demanded for clinical applications. In this study, we demonstrated the use of a relatively simple processing route based on preparation of silver-doped CPCs (CPCs-Ag) through the preparation of solid dispersed active powder phase. Real-time monitoring of structural transformations and kinetics of several CPCs-Ag formulation...

Objective(s): In positron emission tomography (PET) studies, thoracic movement under free-breathing conditions is a cause of image degradation. Respiratory gating (RG) is commonly used to solve this problem. Two different methods, i.e., phase-gating (PG) and amplitude-gating (AG) PET, are available for respiratory gating. It is important to know the strengths and weaknesses of both methods when...