GARDASIL has been shown to reduce the incidence of pre-cancerous cervical, vulvar, and vaginal lesions, and external genital warts causally related to HPV6/11/16/18. Because of its expected public health benefit on reduction of cervical cancer and other HPV-related diseases, this vaccine has been rapidly implemented in the routine vaccination programs of several countries. It is therefore essen...

In a large health insurance database, incidence of anogenital warts among 15 to 19 years old females decreased from 316/100,000 person-years in 2007 to 242 in 2008 (23% reduction, p=0.0001). The decrease started between the 1 and 2 quarter of 2007 (HPV vaccination was introduced in March 2007).

ADP-glucose pyrophosphorylase (AGPase) is the first rate-limiting enzyme in starch biosynthesis and plays crucial roles in multiple biological processes. Despite its importance, AGPase is poorly studied in starchy fruit crop banana (Musa acuminata L.). In this study, eight MaAGPase genes have been identified genome-wide in M. acuminata, which could be clustered into the large (APL) and small (A...

Snail borne infections are of significant importance in livestock production in India especially in eastern Uttar Pradesh. Snails Lymnaea acuminata and Indoplanorbis exustus live in muddy vicinity and standing water and act as the intermediate hosts of the parasitic disease fascioliasis in the livestock. This disease is responsible for significant economic losses due to negative effects to anim...

Chemical investigation of the mycelium of Edenia gomezpompae, a newly discovered endophytic fungus isolated from the leaves of Callicarpa acuminata (Verbenaceae) collected from the ecological reserve El Eden, Quintana Roo, Mexico, resulted in the isolation of four naphthoquinone spiroketals, including three new compounds and palmarumycin CP2 (4). We elucidated the structures of the metabolites ...

OBJECTIVE To determine whether interferon alpha-2a, when utilised as adjuvant chemotherapy following ablation of condylomata acuminata (genital warts) by cryotherapy, is effective in the prevention of recurrences. DESIGN Randomised, placebo-controlled, double-blind study. Statistical analysis was by 2-tailed Fisher's Exact Test. PATIENTS 97 patients with recurrent condylomata acuminata. I...

OBJECTIVE To determine whether patients with condylomata acuminata have an increased risk of developing cancer. DESIGN Prospective cohort study on patients diagnosed as having condylomata acuminata. The number of malignant tumours in the cohort was compared with national incidences obtained from the Swedish Cancer Registry. SETTING Dermatology department of the Karolinska Hospital, Stockhol...

Two cases of umbilical warts are described. The occurrence of these lesions was not previously known. In both cases there was a history of long-standing genital warts.

An age-based pattern of human papillomavirus (HPV) was observed among unvaccinated women in Australia, with a second peak occurring when women were in their early 50s. A similar age-based pattern for genital warts was also observed among unvaccinated Australian women, with the first peak (8.4%) occurring at age 15-20 years, which then declined gradually to 4.8% when women were aged 41-45 years;...