The diagnosis of polycythaemia vera (PV) has been established upon sets of clinical criteria, which require the presence of absolute erythrocytosis (AE). The most recent clinical criteria for PV, published by the World Health Organization (WHO) in 2001, also required AE, and stated that the measured red cell mass (RCM) could be replaced by a surrogate marker for AE; a haemoglobin (Hb) value of ...

HIV-1 subtype CRF01-AE predominates in south Asia and has spread throughout the world. The virus tropism must be determined before using CCR5 antagonists. Genotypic methods could be used, but the prediction algorithms may be inaccurate for non-B subtypes like CRF01-AE and the correlation with the phenotypic approach has not been assessed. We analyzed 61 CRF01-AE V3 clonal sequences of known phe...

BACKGROUND In 2013-2014, French Polynesia experienced for the first time a Zika outbreak. Two Aedes mosquitoes may have contributed to Zika virus (ZIKV) transmission in French Polynesia: the worldwide distributed Ae. aegypti and the Polynesian islands-endemic Ae. polynesiensis mosquito. METHODOLOGY/PRINCIPAL FINDINGS To evaluate their vector competence for ZIKV, mosquitoes were infected per o...

Optical spectral variability of quasars and BL Lac Objects is compared by means of the spectral variability parameter β (Trevese & Vagnetti 2002). Both kinds of objects change their spectral slopes α, becoming bluer when brighter, but BL Lac Objects have smaller β values and are clearly separated from quasars in the α − β plane. Models accounting for the origin of the variability are discussed ...

Cystic fibrosis (CF), the most common life-shortening genetic disorder in Caucasians, affects approximately 70 000 individuals worldwide. In 1998, the Cystic Fibrosis Foundation (CFF) launched the CF Therapeutics Development Network (CF-TDN) as a central element of its Therapeutics Development Programme. Designed to accelerate the clinical evaluation of new therapies needed to fulfil the CFF mi...

Plasmodium falciparum proteins that bind to the putative erythrocyte receptor (glycophorin) have been identified in several laboratories by their ability to bind to glycophorin immobilized on aminoethyl-BioGel (AE-BioGel). We here report that several parasite proteins bind to AE-BioGel in the absence of coupled glycophorin. Binding is apparently due to the strong ion-exchange properties of the ...

Citation: Nardi T, Hammerquist C, Nairn JA, Karimi A, Månson J-AE and Leterrier Y (2015) Nanoindentation of functionally graded polymer nanocomposites: assessment of the strengthening parameters through experiments and modeling. Front. Mater. 2:57. doi: 10.3389/fmats.2015.00057 Nanoindentation of functionally graded polymer nanocomposites: assessment of the strengthening parameters through expe...