PURPOSE Pharmacovigilance Research Network built a spontaneous reporting system and collected adverse drug reactions (ADRs) by electronic submission (e-sub) in Korea. We analyzed ADRs spontaneously reported through e-sub from regional health professionals. MATERIALS AND METHODS Nine hundred and thirty three ADR cases were collected and analyzed from January to December in 2008. "A matter" was...

Tenofovir is an antiviral agent prescribed for patients suffering from hepatitis B. It is associated with some side effects such as reduction in the level of patients’ adherence. The aim of this study was to evaluate the impact of clinical pharmacist consultation on patients’ adherence to the use of Tenofovir. In this prospective study, a total of 80 patients were enrolled into the study and we...

Identifying new indications for existing drugs (drug repositioning) is an efficient way of maximizing their potential. Adverse drug reaction (ADR) is one of the leading causes of death among hospitalized patients. As both new indications and ADRs are caused by unexpected chemical-protein interactions on off-targets, it is reasonable to predict these interactions by mining the chemical-protein i...

introduction: amodiaquine is a partner drug in the artemisinin-based combination therapy artesunate-amodiaquine. reports of the adverse drug reaction known as amodiaquine-associated asthenia are scarce, and this adverse reaction needs to be investigated in detail. this article presents and reviews a case of amodiaquine-associated asthenia. a literature search for the characteristics of this adv...

Adverse drug reactions (ADRs) are one of the leading causes of mortality in health care. Current ADR surveillance systems are often associated with a substantial time lag before such events are officially published. On the other hand, online social media such as Twitter contain information about ADR events in real-time, much before any official reporting. Current state-of-the-art in ADR mention...

Background: Budesonide foam 2 mg twice daily induced complete mucosal healing in patients with mild-to-moderate ulcerative colitis (UC) a phase 3 study. Post-marketing surveillance is underway to assess the real-world outcomes UC patients.Research design and methods: The authors performed an interim analysis of post-marketing 182 who received budesonide rectally.Results: was prescribed 76.4% fo...

OBJECTIVES To describe a nationwide system for postmarketing follow up of new antirheumatic drugs in Sweden, and to analyse safety and effectiveness in an etanercept treated patient cohort. METHODS Etanercept became available in Sweden for prescribing on a named patient basis in 1999. All patients treated were included in a follow up of intensified adverse event reporting and recording of cli...

Adverse drug reactions (ADRs) constitute a huge burden on health systems, and medication errors (MEs) are the most common preventable cause of adverse drug events. In developed countries pharmacists contribute to a great extent in ADR monitoring and reporting, improving patient quality of care and safety. This review aims to explore pharmacists’ practices and views on ADR reporting, extent and ...

Medical research aims to discover more about health and to find new ways to treat or prevent diseases[1]. The beneficial medicines can cause side effects, which is why they are monitored for safety. Safety issues arise whenever medical choices have to be made[2]. During the period of treatment, prescribed drugs produce certain effects other than the desired or expected effects. These are genera...