PURPOSE Crohn's disease is a type of inflammatory bowel disease affecting estimated 4 million people worldwide. Therapy stratification of Crohn's disease (CD) is mainly based on the inflammatory activity being assessed by endoscopic biopsy and clinical criteria. Cross-sectional imaging allows for the assessment of structural characteristics of the entire gastrointestinal tract including small b...

To the Editor: Solitary splenic non-Hodgkin’s lymphoma (SSNHL) is a rare primary neoplasm; with an incidence less than 1% [1-3]. Authors have stated that solitary splenic lymphoma shows diffuse red pulp infiltration and enlargement without mass formation [1]. It cannot be pointed out by plain computed tomography (CT) or magnetic resonance imaging (MRI), ultrasounography (US) or Gallium-67 citra...

Case Report A 52-year-old woman without a significant past medical history presented to her primary care physician in July 2011 for evaluation of a large, nontender, firm, fixed left inguinal mass. A computed tomography (CT) scan of the abdomen and pelvis confirmed bulky left inguinal adenopathy measuring up to 5.6 cm and numerous left iliac nodes measuring up to 4.7 cm, but was otherwise negat...

malignant lymphoma is the neoplastic transformation of cells, mostly originating from lymphoid tissues. malignant lymphoma has two major subtypes: hodgkin and non-hodgkin lymphoma. malignant lymphoma is the most common neoplasm in 3rd and 4th decades of life and more than two third of affected patients presented painless peripheral lymphadenopathy. involvement of waldeyer’s ring, epitrochlear a...

kimura’s disease (kd) is a chronic inflammatory disorder primarily seen in male asians during the second and third decades of life. clinically, it presents as solitary or multiple subcutaneous nodules, predominantly in the head and neck region, typically in the pre auricular region, forehead, and scalp. the etiology of kimura disease is still unknown. this disorder should be suspected when the ...

Background: Epstein-Bar virus (EBV) causes infectious mononucleosis in more than 90% of children. Rarely, mononucleosis may lead to malignancy. The aim the current study was to introduce a child with mononucleosis and persistent adenopathy. Case report: A 4-year-old male patient presented with complaints of fever, shortness of breath and sore throat. He was treated with antibiotics and prednis...

CASE REPORT A 78-year-old man presented with a new growth in his right testis which was uncomfortable, but not painful. He reported a progression in growth over the past few months, and stated that it was doubled in size in the previous month. His past medical history included mumps as a child, hypertension, and recurrent urolithiasis with reported spontaneous passage of calcium oxalate calculi...

We report a challenging case of a 16-year-old male who presented with thrombocytopenia and eluded a definitive diagnosis for over 2 years. He was initially diagnosed with a viral illness, although he later developed adenopathy and splenomegaly. An evaluation by an oncologist was unrevealing. He worked on a farm with livestock exposure and was later diagnosed with an atypical, zoonotic infection...