OBJECTIVE To determine the diagnostic utility of adenosine deaminase (ADA) in exudative pleural effusions of different etiologies. SETTING AND DESIGN It was an observational study conducted at a tertiary care teaching institute. MATERIALS AND METHODS Of a total of 171 pleural fluid samples, 122 were found to be exudates and were included in the study. Pleural fluid ADA was done for all incl...

Mice with three amino acid mutations in the calmodulin binding domain of type-2 ryanodine receptor ion channel (Ryr2(ADA/ADA) mice) have impaired intracellular Ca(2+) handling and cardiac hypertrophy with death at an early age. In this report, the role of signaling molecules implicated in cardiac hypertrophy of Ryr2(ADA/ADA) mice was investigated. Calcineurin A-β (CNA-β) and nuclear factor of a...

BACKGROUND No consensus on definitions of prediabetes exists among international organisations. Analysis of associations with different definitions and clinical complications can inform the comparative value of different prediabetes definitions. We compared the risk of future outcomes across different prediabetes definitions based on fasting glucose concentration, HbA1c, and 2 h glucose concent...

OBJECTIVE To establish the adenosine deaminase (ADA) activity in women who had been pregnant with a child suffering from central nervous system (CNS) anomaly. METHODS The study group comprised 68 women who had been pregnant with an affected child, and 68 controls matched for age, gestational age and body mass index. Maternal venous blood was collected for measurement of ADA levels. We defined...

BACKGROUND Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax. MATERIAL AND METHODS Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; periphera...

The tree width of a graph G measures how close G is to being a tree or a series-parallel graph. Many well-known problems that are otherwise NP-complete can be solved efficiently if the underlying graph structure is restricted to one of fixed tree width. In this paper we prove that the tree width of goto-free Ada programs without labeled loops is ≤ 6. In addition we show that both the use of got...

We employed intracoronary infusions of calf intestine adenosine deaminase (ADA) to test the hypothesis that adenosine regulates coronary blood flow during myocardial reactive hyperemia (RH). Infusions of 4.5 U ADA/min per kg body weight into the left circumflex coronary artery of 10 open-chest dogs reversibly reduced repayment of flow debt by 30-39% (P less than 0.05) following 5-, 10-, 15-, 20...

BACKGROUND The diagnosis of tuberculous meningitis (TBM) can be extremely difficult in the absence of culture confirmation. Cerebrospinal fluid (CSF) adenosine deaminase (ADA) can potentially assist in this regard, although its current value remains unclear. The literature on the usefulness of CSF ADA in TBM diagnosis is inconsistent, especially from an analytical point of view. METHODS A ret...

Adenosine deaminase (ADA), an enzyme essential for the differentiation of lymphoid cells, has been used for monitoring diseases with altered immunity. The purpose of this study was to investigate the changes in serum ADA activity throughout normal pregnancy. We measured the catalytic values of serum ADA from 202 normal pregnant women using a commercial kit. Subjects were divided into four group...

In this paper we investigate the interactions between artificial intelligence and Ada. The Ada language has been mandated for use in all U.S. Department of Defense mission critical embedded systems. Artificial intelligence has become an important ingredient in such systems. Currently, LISP is the language of choice among DoD AI implementors, and its continued use may retard the expected widespr...