Results We studied 119 patients. Mean age: 44.42 ± 13.85 years. Drug intoxication in 77.3% of patients, alcohol in 16.8% and caustic 9.2%. 78.3% was a suicide attempt. The mean Glasgow Coma Scale in 72.5% were < 8 points. 69.7% required mechanical ventilation. The mortality of patients hospitalized for caustic ingestion was 54.5% and 1.9% in the rest (p < 0.001). The multivariate analysis showe...

Methods Single centre observational retrospective study in a 14-bed Intensive Care Unit of a University Hospital. All haematological patients admitted between January-2009 and December-2014 were enrolled. Data acquired included: demographics characteristics, haematological diagnosis, reason of ICU admission, severity-of-illness scores (APACHE and SOFA) and intensive care therapy (mechanical ven...

The risk factors for and presentation of Candida tropicalis fungemia, in comparison with those of Candida albicans, have been incompletely characterized. We compared 43 cases of C. tropicalis fungemia with 148 cases of C. albicans fungemia. In univariate analysis, patients with C. tropicalis fungemia were more likely to have leukemia (P=.0006), prolonged neutropenia (P=.03), and a positive bloo...

BACKGROUND Functional status (FS) before intensive care unit (ICU) admission is associated with short-term and long-term outcomes among critically ill patients. However, measures of FS are generally not integrated into ICU-specific mortality prediction models. METHODS This retrospective cohort study used prospectively collected data from 9638 consecutive patients admitted to a single ICU betw...

Objectives We aim to explore differences in mortality between patients admitted during working hours (8am-5pm on weekdays and 8am-11am on weekends) compared to those admitted after hours. Methods This is a retrospective cohort study of admissions to a medical ICU in a tertiary teaching hospital between 2010-2014. All patients with known APACHE II scores were analysed. Primary outcome measure wa...

STUDY OBJECTIVE To validate the APACHE (acute physiology and chronic health evaluation) III unadjusted and similar hospital mortality estimate models on 30-day mortality, and to propose a simple approach to modeling local 30-day in-hospital mortality of critically ill hospitalized adults for quality management and risk-adjusted monitoring. DESIGN Noninterventional, observational study. PATI...

STUDY OBJECTIVE Evaluation of the performance of the APACHE (acute physiology and chronic health evaluation) III ICU and hospital mortality models at an Australian tertiary adult ICU. DESIGN Noninterventional, observational study. SETTING Metropolitan, Australian, tertiary referral medical/surgical ICU. PATIENTS A total of 3,398 consecutive eligible admissions from January 1, 1995, to Dec...

The impact of antimicrobial treatment on the outcome of carbapenem nonsusceptible Klebsiella pneumoniae (CnsKP) infections needs to be elucidated. This nationwide, multicenter study was conducted to evaluate the impact of appropriate antimicrobial therapy on 14-day mortality among patients with CnsKP infection in Taiwan.Patients with CnsKP infections from 11 medical centers and 4 regional hospi...

Results 343 patients were included, 158 (46.1%) with secondary and 185 (53.9%) with tertiary peritonitis. 64.4% were male, age was 63.7 ± 14.3 years and APACHE was 19.4 ± 7.8. In-hospital mortality was 37%. We showed a higher incidence of Candida spp. (Odds Ratio(OR):1.275;95% Confidence Interval(CI):1.096-1.789;P=0.016), Enterococcus faecium (OR:1.085;95% CI:1.018-1.400;P=0.002) and Enterococc...

BACKGROUND The occurrence of highly resistant microorganisms (HRMOs) is a major threat to critical care patients, leading to worse outcomes, need for isolation measures, and demand for second-line or rescue antibiotics. The aim of this study was to quantify the burden of HRMOs in an intensive care unit (ICU) for adult patients in a university hospital in the Netherlands. We evaluated local dist...