OBJECTIVES This study aimed to examine the association between fluvastatin use and acute pancreatitis in Taiwan. METHODS Using the database from the Taiwan National Health Insurance (NHI) Program, we designed a case-control study which consisted of 3501 individuals aged 20-84 with new at-the-time diagnoses acute pancreatitis as the case group and 8373 randomly selected individuals without acu...

The use of prophylactic antibiotics in patients with severe acute pancreatitis remains an intensely debated topic. Although animal studies consistently demonstrated an advantage of antibiotic prophylaxis, the only two blinded randomized controlled trials could not confirm these findings. Translation of the experimental models in human clinical practice is hampered by a number of fundamental dif...

Infected necrosis is a potentially fatal complication of necrotizing pancreatitis. Open surgical debridement is the mainstay management of infected pancreatic necrosis. Over the last decade minimally invasive techniques have been increasingly used for the treatment of infected pancreatic necrosis and their results are encouraging. However, the optimal technique of minimal access necrosectomy an...

A 12-year-old girl presented with acute abdominal pain and vomiting. Raised serum amylase with the radiological findings supported a diagnosis of acute pancreatitis. Subsequent investigation confirmed celiac disease. Very few children with celiac disease present with an acute pancreatitis. The mechanism by which celiac disease is associated with pancreatitis is discussed here.

IntroductIon Acute pancreatitis is an acute inflammatory process of the pancreas, which has variable involvement of other regional tissues and/or remote organ systems. The disease can be classified as mild or severe depending on the extent of inflammation and organ involvement. Mild pancreatitis consists of interstitial (edematous) pancreatitis on imaging with minimal or no extrapancreatic orga...

CONTEXT Propofol can cause acute pancreatitis related to hypertriglyceridemia, however, other mechanisms may also exist. CASE REPORT A 71-year-old male on propofol infusion in the intensive care setting, developed acute pancreatitis as confirmed biochemically and by imaging. He did not have any elevation of triglycerides and on propofol re-challenge, had recurrence of pancreatitis with the ab...

Diagnosis of pancreatitis is based on the determination of serum amylase and lipase levels. However, recent identification of specific leptin receptors in the pancreas suggests that this peptide may also play some roles in the modulation of pancreatic function. The objective of the present study was to investigate the relationship between serum leptin levels and pancreatitis. Thirty male Wistar...

CONTEXT Neurological complications following an acute attack of pancreatitis have been described. They are mainly in the form of encephalopathy, retinopathy and rarely polyneuropathy. Cerebral infarction following an acute attack of pancreatitis is very rare. CASE REPORT We report the case of a 25 year old male, who developed multiple cerebral infarcts (both hemorrhagic and non-hemorrhagic) a...

Aim. Acute pancreatitis is typically a mild disease, but some patients develop severe courses. Fatty liver changes are seen in patients with acute pancreatitis, but its clinical significance has not been well-studied. We aimed to investigate the relationship between fatty liver and the severity of acute pancreatitis. Methods. Unenhanced CT images of patients with acute pancreatitis were retrosp...