Myopia continues to be a serious public health problem due the steady increase in prevalence of disease and presence complications leading loss vision. The aim study was investigate myopia among medical students. Materials methods. A self-reported questionnaire used collect myopia-related data 1st-6th year students various faculties Kazan State Medical University. assessed using record patient ...

Purpose To identify causal gene mutations in 14 families with autosomal dominant (AD) high myopia using exome sequencing. Methods Select individuals from 14 large Caucasian families with high myopia were exome sequenced. Gene variants were filtered to identify potential pathogenic changes. Sanger sequencing was used to confirm variants in original DNA, and to test for disease cosegregation in...

PURPOSE Myopia, or near-sightedness, is one of the most common human visual impairments worldwide, and high myopia is one of the leading causes of blindness. In this study, we investigated the mutation spectrum of ZNF644, a causative gene for autosomal dominant high myopia, in a high-myopia cohort from a Chinese population. METHODS DNA was isolated with the standard proteinase K digestion and...

AIMS To assess the longitudinal changes in biometric parameters and associated factors in young myopic children aged 7--9 years followed prospectively in Singapore. METHODS Children aged 7--9 years from three Singapore schools were invited to participate in the SCORM (Singapore Cohort study Of the Risk factors for Myopia) study. Yearly eye examinations involving biometry measures were perform...

While instrument myopia is known to occur when microscopes are used, little is known about the accommodation response during microscopy, or about the factors which may alter the magnitude of instrument myopia. In addition, there has been no real-time objective measurement of instrument myopia during the microscopy task. Twenty inexperienced subjects and 10 experienced microscopists (average wor...

The available evidence suggests that both genes and environment play a crucial role in the development of juvenile onset myopia. When the human visual system is examined from an evolutionary perspective, it becomes apparent that humans, living in the original environmental niche (hunter-gatherer) for which our species is genetically adapted, are either slightly hypermetropic or emmetropic and r...

The incidence of myopia is constantly on the rise. Patients of high myopia and pathological myopia are young and can lose vision due to a number of degenerative changes occurring at the macula. With the emergence of new technologies such as swept-source optical coherence tomography (OCT) and OCT angiography, our understanding of macular pathology in myopia has improved significantly. New condit...

PURPOSE To determine the prevalence and associations of myopia in schoolchildren in provincial Western China. METHODS In the school-based observational cross-sectional Gobi Desert Children Eye Study, cylcoplegic refractometry as part of a comprehensive ophthalmic examination was performed in all schools in the oasis region of Ejina. Out of 1911 eligible children, 1565 (81.9%) children with a ...

PURPOSE Myopia is a global public health issue; however, no information exists as to how potential myopia retardation strategies are being adopted globally. METHODS A self-administrated, internet-based questionnaire was distributed in six languages, through professional bodies to eye care practitioners globally. The questions examined: awareness of increasing myopia prevalence, perceived effi...

purpose: to evaluate the visual outcomes of lasik in myopic eyes. methods: this interventional case series was performed on records of 345 eyes of 179 patients for correcting myopia with astigmatism < 3.00 diopter (d). all patients were operated by one surgeon (h.n.) with the nidek ec 5000 excimer laser. all patients had at least one year follow up. based on preoperative refraction, patients we...