OBJECTIVE To determine the frequency, etiology (viral infection or vaccination), presenting signs and symptoms, response to therapy, complication and course of acute disseminated encephalomyelitis (ADEM) in our hospitals. METHODS A 2-year retrospective, descriptive, chart review of children with final diagnosis of ADEM in 2 hospitals (Hazrat Rasool and Mofid in Tehran, Iran during 2000-2002) ...

PURPOSE To review the frequency, distribution, and extent of deep gray matter disease in children with acute disseminated encephalomyelitis. METHODS The MR examinations of 10 patients, who were discharged with the clinical diagnosis of acute disseminated encephalomyelitis between 1986 and 1992, were retrospectively reviewed. Locations of abnormal signal in the cerebral and cerebellar cortices...

Mice with severe combined immunodeficiency (SCID) were injected intravenously with primary bone marrow blasts from 12 children with newly diagnosed t(4;ll)(q21;q23) acute lymphoblastic leukemia (ALL). Blasts from eight patients caused overt disseminated leukemia, whereas blasts from the other four patients produced occult leukemia that was detectable only by the polymerase chain reaction (PCR) ...

It was confirmed by zymographic technique that 1 ml of normal human plasma possessed about 0. 2 IU of urokinase activity which is a high molecular weight form with a molecular weight of 53, 000. Plasma of an acute pancreatitis patient followed by disseminated intravascular coagulation possessed the same amount of urokinase activity as normal plasma, and was confirmed to be composed of two types...

BACKGROUND AND PURPOSE White matter lesions on MR images obtained from patients with acute disseminated encephalomyelitis (ADEM) have been reported to appear shortly after symptom onset, and their resolution has been claimed to parallel recovery. To elucidate the temporal evolution of these lesions and to associate the changes on MR images to the patients' clinical condition, we performed seria...

1434 The MG Composite: A valid and reliable outcome measure for myasthenia gravis T.M. Burns, M. Conaway, and D.B. Sanders, on behalf of the MG Composite and MG-QOL15 Study Group 1441 Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1 E.L. Logigian,W.B.Martens,R.T.Moxley IV, M.P.McDermott,N.Dilek,A.W.Wiegner,A.T. Pearson, C.A.Barbieri, C.L. Annis,C.A. Thornton, andR....

症 例 症例1:38歳,男 性.主 訴:意 識 障害.既 往 歴:10歳 気管 支喘息.家 族歴:父 が糖尿病 と大 腸癌.母 が糖 尿病 と胆嚢癌.現 病歴:2002年12 月末 より発熱,頭 痛があ り,翌 年1月 初旬 に尿 閉 と意識障害が出現 し当院を受診 し入院 となっ た.入 院時現症:体 温38.1度以 外は一般 身体所 見 に異常は なかった.意 識障害(JCS3)と 項部 硬直,両 下肢の腱 反射低下 を認めた.病 的反射 は陰性 であった.5日 後の歩行 は失調性で,両 下 肢の ジンジ ンした しびれ を訴え,Th7以 下の表 在感覚低 下 と尿 閉を呈 した.入 院時検査:WBC 6,400/μl,CRP0.9mg/dl.髄 液はキサ ン トクロ ミーを呈 し,細 胞数307/mm3(多 核球67,リ ン パ 球240),蛋 白204mg/dl,糖47mg/...

The severe acute respiratory syndrome coronavirus 2, the virus that causes disease 2019 caused a worldwide pandemic and became massive problem in our healthcare system. This infection has broad clinical presentation from asymptomatic to symptoms, unfortunately death. Hypercoagulability associated with this can cause significant morbidity, increased risk of microthrombosis, vascular hyperpermeab...

BACKGROUND Procalcitonin has been advocated as a marker of bacterial infection, so this study was carried out to determine the usefulness of serum procalcitonin in the early diagnosis of urosepsis. METHODS The subjects were 37 febrile patients with urinary tract infection in whom we examined the serum procalcitonin concentration at the start of treatment. RESULTS Thirty patients had acute p...

Pulmonary coccidioidomycosis is a fungal disease endemic to the desert regions of the southwestern United States, Mexico, Central America, and South America. The incidence of reported disease increased substantially between 1998 and 2011, and the infection is encountered beyond the endemic areas because of a mobile society. The disease is caused by inhalation of spores of Coccidioides species. ...