Bioavailability is the rate and extent to which the active ingredient or active moiety is absorbed from a drug product and becomes available at the site of action. For drug products that are not intended to be absorbed into the bloodstream, bioavailability may be assessed by measurements intended to reflect the rate and extent to which the active ingredient or active moiety becomes available at...

Safranal is a monoterpene aldehyde found in saffron (Crocus sativus L.) petals. It has been previously reported that safranal has a wide range of activities such as antioxidant and anti-inflammatory effects. In this study, we examined the effect of safranal on brain injuries in a transient model of focal cerebral ischemia. Transient focal cerebral ischemia was induced by middle cerebral artery ...

BACKGROUND Thermogenic (TRM) supplements are often used by people seeking to decrease body weight. Many TRM supplements are formulated with multiple ingredients purported to increase energy expenditure and maximize fat loss. However, in the past some TRM ingredients have been deemed unsafe and removed from the market. Therefore, it is important to verify the safety of multi-ingredient TRM suppl...

The aim was to characterize the effect of over-the-counter whitening strips on proteins in teeth. active ingredient is Hydrogen Peroxide.

This paper discusses the nature of the active ingredient of homeopathic ultramolecular dilutions in terms of quantitative physics. First, the problem of the nature of an active ingredient in ultramolecular dilutions is analysed leading to the recognition of the necessity of characterizing the active ingredient as a non-local quality. Second, non-locality in quantum mechanics, which is used as a...

Diphacinone treated oat groats were effective in reducing populations of California ground squirrels (Spermophilus beecheyi) by more than 84%. Two concentrations of active ingredient (0.005% and 0.01%) were compared, as well as two application methods: spot baiting and bait stations. Squirrel activity on test plots was assessed before and after bait applications using visual counts and active b...

In this study near-infrared (NIR) transmission and diffuse reflection spectra of tablets with two different pharmaceutical active substances in variable concentrations were recorded. The purpose of these tests was to correlate the spectra with the content of active ingredient, hardness and moisture content in order to implement a fast, non-destructive quality control of solid drug formulations ...

Since 24 states and the District of Columbia have legalized marijuana in some form, suppliers of legal marijuana have developed Cannabis sativa products for use in electronic cigarettes (e-cigarettes). Personal battery powered vaporizers, or e-cigarettes, were developed to deliver a nicotine vapor such that smokers could simulate smoking tobacco without the inherent pathology of inhaled tobacco...

A new semi-selective medium, acidified weak potato-dextrose agar (AWPDA) with Mertect (active ingredient: thiabendazole), was developed for the isolation and enumeration of Alternaria species from samples of soil and plant debris. The medium was selected based on growth inhibition tests against Alternaria and several other commonly encountered saprobic fungi utilizing three antifungal agents, B...

Excipients are included in dosage forms to aid manufacture, administration or absorption. Other reasons for inclusion concern product differentiation, appearance enhancement or retention of quality.1 They rarely, if ever, possess pharmacological activity and are accordingly loosely categorized as ‘inert.’ However, excipients can initiate, propagate or participate in chemical or physical interac...