OBJECTIVE To compare the pediculicidal activity of Ovide lotion and its active ingredient, 0.5% malathion, with Nix and its active ingredient, 1% permethrin, in permethrin-resistant head lice. DESIGN In vitro pediculicidal product and active ingredient comparison. The presence of knockdown resistance-type mutations (T929I and L932F) was validated by DNA sequencing. SETTING University of Mas...

This paper describes a fully-automated system (AUTO DISS((R))) for the determination of active ingredient release of solid oral dosage forms according to the paddle method of the US Pharmacopoeia (USP) and European Pharmacopoeia.Twenty batches can be tested continuously, with the six individuals (tablets, capsules etc.) of one batch being examined synchronous. The components of the AUTO DISS((R...

The herbicide bentazon (CASRN 25057-89-0) is extensively used in agriculture in Brittany (France) to replace atrazine. Bentazon is not readily adsorbed by soil and therefore it enters adjacent freshwater ecosystems, making its way to estuarine and marine waters areas. Information regarding its effects on marine ecosystems is scarce. Phytotoxicity assessments were conducted in the laboratory on ...

An aerosol formulation containing 7.5 mg of R-salbutamol sulfate was developed. The aerosol was nebulized with an air-jet nebulizer, and further assessed according to the new European Medicines Agency (EMA) guidelines. A breath simulator was used for studies of delivery rate and total amount of the active ingredient at volume of 3 mL. A next generation impactor (NGI) with a cooler was used for ...

S-[(4-chlorophenyl) methyl]diethylcarbamothioate General information This document reviews the environmental fate and environmental effects of the thiocarbamate herbicide, thiobencarb {S–[(4-chlorophenyl) methyl] diethylcarbamothioate (C 12 H 16 ClNOS)}. Thiobencarb, also referred to as benthiocarb was developed by Kumiai Chem. Ind. Co. Ltd and introduced in the market in 1970 (Ishikawa, 1981)....

The paper presents a dropwise additive manufacturing process for pharmaceutical products (DAMPP) as an alternative to conventional methods. This mini manufacturing process for the production of personalized pharmaceutical products utilizes drop-on-demand (DoD) printing technology for the deposition of active pharmaceutical ingredient (API) onto edible substrates. Here we present a process contr...

After much anticipation, approval of the first U.S. biosimilar medications may be around the corner. Biosimilars hold the promise of reducing healthcare spending by offering lower-cost alternatives to highpriced biologic drugs. Biosimilars are not generic versions of existing biologics, however. Generic medications contain an active ingredient identical to that in the reference (‘‘brandname’’) ...

4. We assign a number of milligrams to each product, according to the strength of its primary active ingredient. To do so, we combine the descriptive data in the Nielsen dataset with the data of milligrams of a speci…c active ingredient in a speci…c formula. In the case of Ibuprofenand Naproxen Sodiumbased pain relievers, the assignment was straightforward, since these OTC products can come onl...

C17H17ClO 6 M.W. 352.77 Griseofulvin, USP occurs as a white to creamy white, odorless powder which is very slightly soluble in water, soluble in acetone, dimethylformamide, and chloroform and sparingly soluble in alcohol. Each Gris-PEG tablet contains: Active Ingredient: griseofulvin ultramicrosize................................................. 125 mg Inactive Ingredients: colloidal silicon d...

Spray-dried plasma (SDP) or spray-dried serum (SDS) are ingredients that are collected and processed to preserve the functional characteristics of the proteins. Spray-dried plasma or serum is a diverse mixture of functional components consisting of immunoglobulins, albumin, fibrinogen, lipids, growth factors, biologically active peptides (defensins, transferrin), enzymes and other factors that ...