نتایج جستجو برای: aconitine

تعداد نتایج: 298  

2017
Wanzhen Jiang Mengliu Zeng Zhenzhen Cao Zhipei Liu Jie Hao Peipei Zhang Youjia Tian Peihua Zhang Jihua Ma

Icariin, a flavonoid monomer from Herba Epimedii, has confirmed pharmacological and biological effects. However, its effects on arrhythmias and cardiac electrophysiology remain unclear. Here we investigate the effects of icariin on ion currents and action potentials (APs) in the rabbit myocardium. Furthermore, the effects of icariin on aconitine-induced arrhythmias were assessed in whole rabbit...

2010
G. N. MOZHAYEVA A. P. NAUMOV B. I. KHODOROV

Application of 10 5 mol/1 batrachotoxin (BTX) to the voltage-clamped node of Ranvier was accompanied by repetitive pulsing (10 Hz, to +60 mV) until almost all the Na channels become modified. Relative permeabilities of modified channels to Na, K and NH4 ions were calculated according to Goldman-Hodgkin-Katz equation (Hodgkin and Katz 1949) from changes in reversal potential caused by equimolar ...

Journal: :American journal of physiology. Heart and circulatory physiology 2003
Alan Kadish David Johnson Willie Choe Jeffrey Goldberger George Horvath

Recent studies have demonstrated that fibrillatory rhythms are not random phenomena but have definable patterns. However, standard mapping techniques may have limitations in their ability to identify the organization of fibrillation. The purpose of this study was to develop and apply a method, "ensemble vector mapping," for characterizing the spatiotemporal organization of fibrillation. Ventric...

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