Introduction. Rosacea is a chronic disease characterized by (depending on the subtype) facial prolonged erythema, sometimes pustules or nodules. Rosacea affects all ages and sex with four subtypes. Pathophysiology aims to many different trigger factors like sun exposure, emotional stress or changed intestinal flora. Studies about Demodex mites according to different authors revealed that they m...

Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matched controls participated in one or a combination of symptom triggering stress...

BACKGROUND Granulomatous rosacea is a rare chronic inflammatory skin disease with an unknown origin. The role of Demodex follicularum in its pathogenesis is currently proved. CASE PRESENTATION We report a case of a 54-year-old Moroccan man with a 3-month history of erythematous, nonpruritic papules on the lateral side around the eyes. Dermoscopy and histology confirmed the diagnosis of granul...

Rosacea is a common skin disorder most often seen in individuals between the ages of 30 and 60. The condition frequently produces erythema, papules, pustules, and edema of midfacial skin. Ocular rosacea occurs in a high percentage of patients, and is a major cause of red eye. A variety of treatments exist that can eliminate pustules, but no therapy is highly effective in eliminating the vascula...

Demodicidosis may present as pityriasis folliculitis, papulopustular lesions, rosacea-like eruptions, and granulomatous rosacea-like eruptions. The diagnosis of demodicidosis made by finding extrafollicular mites in the perifollicular inflammatory infiltrate. The papules resolved after 3 weeks of systemic and topical metronidazole, and low-dose oral prednisolone therapy. In summary, demodex gra...

Inflammatory skin diseases have high prevalence globally and are associated with significant morbidity. We sought to determine whether differences exist in the usage of emergency department (ED) outpatient dermatologic offices between Hispanics non-Hispanic white patients inflammatory disease U.S. In this cross-sectional study, we used nationally representative data from Medical Panel Expenditu...

Rosacea is a common chronic inflammatory facial disorder. Reactive oxygen species (ROS) have key role in the pathogenesis of rosacea. In this study, antioxidant and anti-inflammatory effects bilirubin-based nanoparticles (BRNPs) were investigated LL-37-induced rosacea-like mouse model. Effects BRNPs on skin inflammation ROS level determined using histological analysis. The expression genes enco...

BACKGROUND Disfiguring dermatoses may have a significant impact on patients' quality of life, namely on their relationship with others, self image, and self esteem. Some previous studies have suggested that corrective foundation can improve the quality of life (QOL) of patients with facial dermatoses; in particular, in patients with acne vulgaris or pigmentary disorders. OBJECTIVE The aim of ...