Acne fulminans is a rare and severe form of acne that may evolve from acne vulgaris, especially in male adolescents, or occur as an adverse effect of oral isotretinoin. Arthritis is a serious clinical manifestation when the musculoskeletal system is compromised by AF and has been reported as a rare adverse effect of isotretinoin. Involvement of the sacroiliac joints occurs in 21% of acne fulmin...

Patients with acne often scratch their lesions. As scratching is also a part of the response to pruritic stimuli, this study aimed to determine whether itching accompanies acne. A total of 108 teenagers (mean age 15.8+/-1.8 years) with acne were included in the study. All participants completed a specially designed questionnaire on demographic and clinical data. Itching accompanying acne lesion...

Acne has a prevalence of over 90% among adolescents and persists into adulthood in approximately 12%-14% of cases with psychological and social implications. Possible outcomes of the inflammatory acne lesions are acne scars which, although they can be treated in a number of ways, may have a negative psychological impact on social life and relationships. The main types of acne scars are atrophic...

The moisture content present in human skin makes it look young and the use of moisturizer results in fastening the moisture with a surface film of oil. Acne vulgaris is one of the most commonly seen diseases among the youth. The present study is focused on the use of herbs as moisturizer for acne treatment. The anti-acne moisturizer was formulated from herbal crude extracts and investigated the...

Acne vulgaris remains one of the most common diseases afflicting humanity and it is the skin disease most commonly treated by physicians.[1] It is a disease of the pilosebaceous units, clinically characterized by seborrhea, comedones, papules, pustules, nodules and, in some cases, scarring.[2] Although easy to diagnose, the polymorphic nature of acne vulgaris and its varied extent of involvemen...

resistin (retn), recently found to be relevant to inflammation and inflammatory disorders. we, therefore, aimed to investigate the potential role of retn gene polymorphism in pathogenesis of acne vulgaris with familial history. we investigated the retn-420c/g polymorphism in 180 patients with acne vulgaris and 180 healthy individuals in a case-control association analysis. in this study, we als...

BACKGROUND Acne is a common chronic inflammatory dermatosis of the pilosebaceous unit. It is characterized by seborrhoea, comedone formation and an inflammatory response consistent with defective cellular immunity to Propionibacterium acnes. OBJECTIVES The objective of this study was to investigate the immune reactivity of patients with acne compared with healthy controls by examining the res...

Background: So far seven types of the genus malassezia have been known. Except for one kind, the rest are normal flora of human skin, which under certain circumstances, cause or trigger eleven diseases. One of the side effects of topical and systemic steroid is steroid acne. Objective: This study was conducted to evaluate the association of pityrosporum ovale (Malassezia) and steroid acne...

Epidemiological studies suggest that chocolate increases the incidence and severity of acne. Here we demonstrate that chocolate consumption primes human blood mononuclear cells from volunteers to release more interleukin-1β (IL-1β) and IL-10 upon stimulation with Propionibacterium acne or Staphylcoccus aureus, the two microorganisms involved in the pathogenesis of acne. In contrast, production ...

Acne vulgaris is a disease associated with sebaceous follicle. It starts appearing after the onset of puberty and can extend up to 40-50 years of age. As far as the pathogenesis of acne is concerned, it is not fully understood up till now. Treatment of acne is very frustrating and involves an understanding of etiopathological factors. This review focuses on various factors accountable, pathogen...