BACKGROUND Antimicrobial surveillance is important for providing an up-to-date understanding of the epidemiology of antimicrobial resistance and for creating a forum for rational drug development. In this study, we analyzed antimicrobial test data generated in 2011 by hospitals and commercial laboratories participating in the Korean Nationwide Surveillance of Antimicrobial Resistance program (K...

To reduce the emergence of acquired bacterial resistance, an antimutant dosing strategy using the mutant prevention concentration (MPC) has been advocated (7, 8). Recently, Drlica and collaborators showed that there was a low correlation between MIC and MPC when Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae were tested again...

Acinetobacter radioresistens strain SA188 is a plant endophytic bacterium, isolated from root nodules of the desert plants Indigofera spp., collected in Jizan, Saudi Arabia. Here, we report the 3.2-Mb draft genome sequence of strain SA188, highlighting characteristic pathways for plant growth-promoting activity and environmental adaptation.

A new national antimicrobial resistance surveillance program in Singapore public hospitals that uses WHONET detected high levels of methicillin resistance among Staphylococcus aureus (35.3%), carbapenem resistance among Acinetobacter spp. (49.6%), and third-generation cephalosporin resistance among Klebsiella pneumoniae (35.9%) hospital isolates in 2006. Antimicrobial drug resistance is a major...

The IMP-4 metallo-beta-lactamase, originally recognized in Acinetobacter spp. from Hong Kong, more recently appeared simultaneously in isolates of the family Enterobacteriaceae from Sydney and Melbourne, Australia. The bla(IMP-4)-qacG2-aacA4-catB3 cassette array was found in isolates from both cities, but in different wider genetic contexts and on different plasmids, suggesting movement of this...

A biochemical model is presented that explains the behaviour of Acinetobacter spp. in enhanced biological phosphorus removal activated sludge systems. The model modifies and extends the proposals of Comeau et al. (1985). Two key parameters are identified in controlling poly-P and PHB synthesis and degradation, the ATP/ADP and NADH/NAD ratios. The predicted behaviour appears to be consistent wit...

The trends and types of carbapenemase-producing Gram-negative bacilli were analyzed from clinical specimens collected between 2005 and 2012 at a Korean teaching hospital. The proportions of carbapenem-resistant Acinetobacter spp. increased markedly to 66%. Metallo-β-lactamase producers significantly decreased and the majority shifted from the bla(VIM-2) type to the bla(IMP-1) type.

An increase in prevalence of multidrug-resistant Acinetobacter spp. in hospitalized animals was observed at the Justus-Liebig-University (Germany). Genotypic analysis of 56 isolates during 2000-2008 showed 3 clusters that corresponded to European clones I-III. Results indicate spread of genotypically related strains within and among veterinary clinics in Germany.

l objective: To test the antimicrobial effectiveness of a silver alginate dressing on opportunistic pathogens, namely meticillin-sensitive Staphylococcus aureus (mSSa) and meticillin-resistant Staphylococcus aureus (mrSa), Klebsiella spp., Enterococcus faecalis, Enterococcus faecium, Pseudomonas aeruginosa, Escherichia coli, Enterobacter sakazakii, Enterobacter cloacae, Serratia marcescens, Chr...

Acinetobacter spp. Bacteremia: A Cohort Study Andrew F. Shorr, MD, MPH; Marya D. Zilberberg, MD, MPH; Scott Micek, PharmD; Marin Kollef, MD; Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC; University of Massachusetts and Evimed Research Group, LLC, Goshen, MA; Pharmacy, Barnes-Jewish Hospital, St. Louis, MO; Pulmonary and Critical Care Medicine, Washington Univ...