Peroxisome proliferator-activated receptor-γ (PPARγ) agonists like pioglitazone (PGZ) are effective antidiabetic drugs, but they induce fluid retention and body weight (BW) gain. Dipeptidyl peptidase IV (DPP IV) inhibitors are antidiabetic drugs that enhance renal Na(+) and fluid excretion. Therefore, we examined whether the DPP IV inhibitor alogliptin (ALG) ameliorates PGZ-induced BW gain. Mal...

The paper describes Physoschistura tigrinum, a new nemacheilid from the Chindwin basin in Manipur, India. The new species is distinguished from congeners in having 91⁄2 branched dorsal-fin rays; 12–14 irregularly arranged light reddish brown bars on the side, some of which are broken into blotches and short bars; 5–6 dark brown saddles; forked caudal fin with 9+8 branched rays; axillary pelvic ...

We have identified a companion to the young planetary-mass brown dwarf Oph 162225-240515. This pair forms a resolved binary consisting of two objects with masses comparable to those of extrasolar giant planets. Several lines of evidence confirm the coevality and youth of the two objects, suggesting that they form a physical binary. Models yield masses of approximately 14 and approximately 7 tim...

We apply Lurie’s theorem to produce spectra associated to 1dimensional formal group laws on the Shimura curves of discriminants 6, 10, and 14. We compute rings of automorphic forms on these curves and the homotopy of the associated spectra. At p = 3, we find that the curve of discriminant 10 recovers much the same as the topological modular forms spectrum, and the curve of discriminant 14 gives...

Two new brominated selinane sesquiterpenes, 1-bromoselin-4(14),11-diene (1) and 9-bromoselin-4(14),11-diene (2), one known cadinane sesquiterpene, cadalene (3), and four known selinane sesquiterpenes, alpha-selinene (4), beta-selinene (5), beta-dictyopterol (6), and cyperusol C (7), were isolated from a sample of marine brown alga Dictyopteris divaricata collected off the coast of Yantai (China...

Striker GE: Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene. Kidney Int Suppl 39: S90–S94, 1993 13. Ibrahim HN, Weber ML: Weight loss: a neglected intervention in the management of chronic kidney disease. Curr Opin Nephrol Hypertens 19: 534–538, 2010 14. Tanner RM, Brown TM, Muntner P: Epidemiology of obesity, the metabolic syndrome, and chronic kidney dis...

BACKGROUND Whole-grain products such as brown rice have been associated with lower risk of metabolic disorders including diabetes. We examined the acceptability and tolerability of substituting brown rice for white rice and the feasibility of introducing brown rice into the diet through a long-term trial to lower the risk of type 2 diabetes. METHODS Fifty-one adults residing in Abuja, Nigeria...

Rates of lipogenesis in foetal isolated brown adipocytes from 22-day-pregnant rats were significantly increased by lactate plus pyruvate as major substrates in the incubation medium, in comparison with the endogenous rates. Insulin stimulated foetal brown-adipocyte lipogenesis, and adrenaline or noradrenaline and isoprenaline decreased lipogenesis. Glucagon had no effect on the lipogenic rate i...

Approved for public release| distribution unlimited. ARPA Order Number 1003 Program Code Number 7M10 Name of Contractor Air Force Office of Scientific Research Date of Contract June 1, 1967 Amount of Contract $197,316.00 Contract Number F44620-67-C-0103 Principal Investigator Glenn H. Brown Telephone Number of Principal Investigato* (216)-672-2654 Contract Expiration Date November 30, 1971 Proj...

The role of social factors in the causation of depression based on the aetiological model proposed by Brown and Harris was examined in a sample of 50 depressed female patients. Loss of mother before age 11 years and lack of confiding relationship was found to act as a vulnerability factor whereas employment status and having three or more children aged 14 or under were not found to have an incr...