BACKGROUND The neuroinflammatory process plays a central role in the initiation and progression of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases, and involves the activation of brain microglial cells. During the neuroinflammatory process, microglial cells release proinflammatory mediators such as cytokines, matrix metalloproteinases (MMP), Reactive oxygen species (ROS)...

the selected parts of four medicinal plants, achillea millefolium, hibiscus rosasinensis, linum usitatissimum and pluchea lanceolata were extracted in absolute methanol to determine their analgesic activity. analgesic activity was assessed on intact mice by tail flick latency via the tail immersion method. the analgesic activities of these plant extracts were compared with acetylsalicylic acid ...

background & aim: osmotic stress in plants lead to increase free radicals and plants use different mechanisms to scavenge these radicals. so, researchers apply stresses especially drought stress to increase secondary metabolites such as phenolics, and antioxidants. one of the valuable medicinal plants is yarrow (achillea tenuifolia) which is a perennial plant with different medicinal applic...

background: achillea talagonica (asteraceae) is an endemic herbaceous plant in iran with small yellow flowers and several times pinnately divided leaves in worm shape. the plant was found to be cytotoxic in our previous studies.   materials and methods: a. talagonica was collected in may 2005 from talegan in north of iran during the full flowering stage. dried aerial parts of the plant were red...

The in vitro antioxidant and antimicrobial activities of the essential oil and methanolic extract of Achillea sieheana Staf. (Asteraceae) were investigated in this study. The chemical composition of the essential oil isolated by hydro-distillation from the aerial parts of A. sieheana was analyzed by GC-MS. Camphor (43.36%), Artemisia ketone (25.95%), 1.8-cineole (6.29%) and camphene (4.77%) wer...

Tannins are an important class of secondary metabolites with a wide range pharmacological effects, due to which they used in various fields treatment. In plants the genus Achillea L., tannins dominant compounds. This allows use plant raw materials and extracts yarrow for development complex herbal combined formulations medicines. The search new sources natural tannin compounds pharmaceutical co...