BACKGROUND There are several options for replacement of the dermal layer in full-thickness skin defects. In this study, we present the surgical outcomes of reconstruction using acellular dermal substitutes by means of objective and subjective scar assessment tools. METHODS We retrospectively reviewed the medical records of 78 patients who had undergone autologous split-thickness skin graft wi...

We study the formation of primordial proto-stars in a ACDM universe using high-resolution cosmological simulations. Our approach includes all the relevant atomic and molecular physics necessary to follow the thermal evolution of a prestellar gas cloud to very high densities. We describe the numerical implementation of the physics. We show the results of a simulation of the formation of primordi...

We study the asymptotic behavior of eigenvalues of large complex correlated Wishart matrices at the edges of the limiting spectrum. In this setting, the support of the limiting eigenvalue distribution may have several connected components. Under mild conditions for the population matrices, we show that for every generic positive edge of that support, there exists an extremal eigenvalue which co...

INTRODUCTION: Pre-pectoral breast reconstruction is an emerging technique with potential benefits that include reduced pain, early patient recovery and no hyperanimation. There are studies reporting on clinical outcomes with pre-pectoral technique [PP] and comparing it to the dual plane technique [DP] in breast reconstruction. The goal of this study is to provide an early assessment of outcomes...

High-resolution functional imaging is providing increasingly rich measurements of brain activity in animals and humans. A major challenge is to leverage such data to gain insight into the brain's computational mechanisms. The first step is to define candidate brain-computational models (BCMs) that can perform the behavioural task in question. We would then like to infer which of the candidate B...

Conventional surgical procedures designed for autogenous tissue material may not be appropriate when using acellular dermal matrix (ADM) for the treatment of gingival recessions. This article describes a new surgical technique that addresses the unique and sensitive aspects of ADM specifically to improve esthetic outcomes and gain increased clinical predictability when treating Miller Class I a...

The last decade has ushered in a rapidly expanding global discussion regarding acellular dermal matrix (ADM) applications, economic analyses, technical considerations, benefits, and risks, with recent emphasis on ADM use in breast surgery. This study aims to evaluate global trends in ADM research using bibliometric analysis. The top nine Plastic Surgery journals were determined by impact factor...

OBJECTIVE Adjunct acellular dermal matrices (ADM) are thought to improve esthetic outcomes of breast reconstruction but the existing evidence is largely anecdotal. In this study, we provide comparative data on esthetic outcomes of expander-implant breast reconstruction with and without ADM. METHODS Chart review was performed on a consecutive series of expander-implant reconstructions by the s...

INTRODUCTION Acellular dermal matrices (ADMs) are now commonly used for breast reconstruction surgery. There are various products available: ADMs derived from human (HADM), porcine (PADM), or bovine (BADM) sources. Detailed long-term follow-up studies are necessary to detect differences in complication rates between these products. MATERIAL AND METHODS From 2010 to 2015, forty-one patients un...

The DCFH assay is commonly used for measuring free radicals generated by engineered nanomaterials (ENM), a well-established mechanism of ENM toxicity. Concerns exist over susceptibility of the DCFH assay to: assay conditions, adsorption of DCFH onto ENM, fluorescence quenching and light scattering. These effects vary in magnitude depending on ENM physiochemical properties and concentration. A r...