نتایج جستجو برای: aceclofenac

تعداد نتایج: 365  

Journal: :Acta pharmaceutica 2009
Santanu Chakraborty Madhusmruti Khandai Anuradha Sharma Ch Niranjan Patra V Jagannath Patro Kalyan Kumar Sen

The purpose of the present research work was to observe the effects of drug solubility on their release kinetics of water soluble verpamil hydrochloride and insoluble aceclofenac from hydrophilic polymer based matrix formulations. Matrix formulations were prepared by the direct compression method. The formulations were evaluated for various physical parameters. Along with the dynamics of water ...

2015
Asif Husain Priyanka Ahuja Aftab Ahmad Shah Alam Khan

The aim of the present study was to synthesize prodrugs of commonly used NSAIDs to overcome the gastrointestinal toxicity (irritation and bleeding) associated with their use. A total of six amide-based prodrugs (Ia-f) of aceclofenac, diclofenac, fenbufen, indomethacin, mefenamic acid and 4-biphenyl acetic acid were synthesized through one-pot method (single step synthesis). The structures of th...

2001
G. P. RILEY

The purpose of this study was to investigate the effects of some commonly used non-steroidal anti-inflammatory drugs (NSAIDs) on human tendon. Explants of human digital flexor and patella tendons were cultured in medium containing pharmacological concentrations of NSAIDs. Cell proliferation was measured by incorporation of 3 H-thymidine and glycosaminoglycan synthesis was measured by incorporat...

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