نتایج جستجو برای: acanthamoeba palestinensis

تعداد نتایج: 2356  

Journal: :Parasitology 2012
Ruqaiyyah Siddiqui Ricky Dudley Naveed Ahmed Khan

The ability of cyst-forming protists such as Acanthamoeba to escape death by transforming into a cyst form, that is resistant to harsh physiological, environmental and pharmacological conditions, has continued to pose a serious challenge to human and animal health. A complete understanding of the fundamental principles of genome evolution and biochemical pathways of cellular differentiation off...

Journal: :Antimicrobial agents and chemotherapy 1984
F L Schuster N Mandel

The phenothiazine compounds trifluoperazine dihydrochloride and chlorpromazine hydrochloride have in vitro activity against the pathogenic free-living amoebae Naegleria fowleri, Acanthamoeba culbertsoni, and Acanthamoeba polyphaga. Drug concentrations of 10 microM were amoebastatic; concentrations of 50 microM were either amoebastatic or amoebicidal. Concentrations of 100 microM were generally ...

Background: Acanthamoeba spp., can cause severe and fatal diseases including encephalitis, skin granulomatous and keratitis. Contaminated waters can be a threat to high risk people such as contact lens wearers, patients with eye surgery or eye trauma, and immunocompromised patients.  Objective: The present study aims to investigate the presence of potentially pathogenic Acanthamoeba in coastal...

Acanthamoeba keratitis (AK) is a sight-threating infection of the cornea that mostly affects contact lens wearers. Until now, AK treatment remains very difficult due to the existence of a highly resistant cyst stage in the life cycle of Acanthamoeba which is extremely resistant to most of the available anti-amoebic compounds. Moreover, current treatment of AK is usually based in the combination...

Background and Aim: Acanthamoeba is a free-living amoebae commonly found in the environmental sources such as soil, water, and dust. This parasite is the causative agent of amoebic keratitis (AK). The objective of the present study was to investigate the presence of Acanthamoeba genotypes in water sources in Bojnurd City. Materials and Methods: Totally, 50 samples of water were taken from diffe...

Journal: :Journal of Biological Chemistry 1973

Journal: :The Journal of antimicrobial chemotherapy 2009
Julia Walochnik Andreas Obwaller Florian Gruber Michael Mildner Erwin Tschachler Miranda Suchomel Michael Duchêne Herbert Auer

OBJECTIVES Acanthamoebae can cause infections of several organs, including eye, skin, lung and brain. Except for Acanthamoeba keratitis, these infections are linked to immunodeficiency. Treatment is generally problematic, due to the lack of sufficiently effective and also easily manageable drugs. In a previous study we discovered that miltefosine (hexadecylphosphocholine) is highly active again...

Journal: :Antimicrobial agents and chemotherapy 2008
Ursula Fürnkranz Markus Nagl Waldemar Gottardi Martina Köhsler Horst Aspöck Julia Walochnik

Acanthamoeba spp. are the causative agents of Acanthamoeba keratitis (AK), which mainly occurs in contact lens wearers, and of skin lesions, granulomatous amoebic encephalitis (GAE), and disseminating diseases in the immunocompromised host. AK therapy is complex and irritating for the eye, skin lesions are difficult to treat, and there is no effective treatment for GAE. Therefore, new anti-Acan...

2012
Beata Kettesy Laszlo Modis Andras Berta Adam Kemeny-Beke

Acanthamoeba keratitis (AK) infection is a rather frequently occurring disease all over the world which can still cause serious or even total loss of vision despite improved diagnostic and therapeutic options. It may cause mostly keratitis, scleritis or chorioretinitis in people with competent immune systems. It mainly affects contact lens wearers with poor hygiene. Corneal trauma due to foreig...

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