Objective(s): This study is aimed to design and synthesize a prodrug of 5-aminosalicylic acid and evaluate its ameliorative effect on experimental ulcerative colitis (UC).Materials and Methods: 5-Aminosalicylic acid-alanine (5-ASA-ALA) was synthesized and characterized. Its stability study was conducted in rat plasma and in the gastroint...

Background: The efficiency of in vitro maturation (IVM) has remained low despite extensive effort to understand the culture conditions. This study investigated the effect of cumulus cells and meiotic inhibitors on oocyte developmental competence in the presence of Alpha Lipoic acid (ALA) Materials and Methods: Mouse germinal vesicle oocytes were considered in cumulus-denuded oocytes (CDOs) and ...

in vitro maturation (ivm) was carried out in the presence of different concentrations (10, 50, 100 or 200 µm) of α-linolenic acid (ala). embryonic cleavage, blastocyst formation following parthenogenetic activation (pa) and in vitro fertilization (ivf), and numbers of total and apoptotic cells in blastocyst were then determine for the 50 μm concentration and compared with the control group. out...

Corresponding Author: Manar Abu Talib Department of Computer Science, University of Sharjah, P.O.Box 27272, Sharjah, UAE Email: [email protected] Abstract: Researchers, practitioners and social scientists all agree on the enormous importance of social science research in advancing human knowledge and informing public policy makers. The National Research Foundation, along with other organ...

Urinary tract infection (UTI) is an extremely common infectious disease. Uropathogenic Escherichia coli (UPEC) is the predominant etiological agent of UTI. Asymptomatic bacteriuric E. coli (ABEC) strains successfully colonize the urinary tract resulting in asymptomatic bacteriuria (ABU) and do not induce symptoms associated with UTI. Oxylipids are key signaling molecules involved in inflammatio...

This proposed study seeks to develop specific e-service (electronic service) strategies that could help enhance competitiveness of Abu Dhabi’s tourism in the global market in general and in the Gulf region in particular. As e-commerce (electronic commerce) increasingly transformed business operations in the contemporary networked economy, services provided by these emerging information and comm...

VanRS two-component regulatory systems are key elements required for the transcriptional activation of inducible vancomycin resistance genes in bacteria, but the precise nature of the ligand signal that activates these systems has remained undefined. Using the resistance system in Streptomyces coelicolor as a model, we have undertaken a series of in vivo studies which indicate that the VanS sen...

Using a fluorometric HPLC method, we determined delta-aminolevulinic acid (ALA) in sera and urine samples from 16 lead workers with blood lead levels ranging from 19 to 107 microG/100 ml. The concentration of ALA in serum correlated highly with the urinary ALA concentration (gamma = 0.957 for ALA mg/1; gamma = 0.967 for ALA mg/g creatinine). The ALA concentrations in the serum of lead workers r...