We established an orthotopic treatment model of prostate cancer to generate reproducible primary and metastatic carcinoma in immunocompetent C57BL/6 mice. Using an in vivo selection scheme of intraprostatic implantation of TRAMP-C1 cells, primary prostate tumors were cultured and recycled three times by intraprostatic injection resulting in the selection and establishment of the recycled cell l...

Thyroid tuberculosis is a very rare condition with rate of 0.1-1.15% even in countries high prevalence tuberculosis. In this presentation, we evaluated the management patient preoperative diagnosis benign tissue and pre-diagnosis multinodular goiter compression symptoms. After thyroidectomy our who had no special history due to detection Langerhans giant cell caseified granuloma-thyroid tubercu...

The effect of radiation on gene expression has been most frequently studied using tissue culture models. To determine the influence of experimental growth condition on radiation-induced changes in gene expression, microarray analysis was done on two human glioma cell lines (U87 and U251) grown in tissue culture and as s.c. or i.c. xenografts. Compared with tissue culture, the number of genes, w...

Case Report A 10 year old female with an 8 year history of a base of tongue mass presented after two months of increasing size and symptoms of dysphagia (Figure 1). Diagnosis of lingual thyroid (and only functional thyroid tissue) was confirmed by thyroid scan. Resection was performed by transoral endoscopic RF ablation (Figures 2,3). Intraoperatively, the total blood loss was 20cc and time for...

Cryopreservation of ovarian tissue has been proposed for storing gametes of young patients at high risk of premature ovarian failure. Autotransplantation has recently provided some promising results and is still the unique option to restore ovarian function from cryopreserved ovarian tissue in humans. In this article, we analyse data from the combined orthotopic and heterotopic transplantation ...

BACKGROUND Ovarian autotransplantation has shown increasing promise as a clinical method for the preservation of fertility and hormonal function. However, information regarding the success rate of this type of transplantation is limited. We hypothesized that results vary according to the site of the ovarian transplantation. To test this hypothesis, fresh or cryopreserved ovarian strips were aut...

Intrathyroidal parathyroid carcinoma is an exceedingly rare cause of primary hyperparathyroidism. A 51-year-old African American female presented with goiter, hyperparathyroidism, and symptomatic hypercalcemia. Sestamibi scan revealed diffuse activity within an enlarged thyroid gland with uptake in the right thyroid lobe suggestive of hyperfunctioning parathyroid tissue. The patient underwent t...