Genes located on the unpaired portion of the humanX chromosome can readily be recognized, but as far as the autosomes are concerned it is not known upon which autosome any human gene is located. The common variety of mongolism is characterized by 21-trisomy, and offers a possible approach to the localization ofhuman autosomal genes. The model on which this approach is based was first formulated...

Background: Vitiligo is a common disease. Its etiology is not known, but 30% of patients have a positive family history. Studies have been done on the influence of ABO and Rh blood groups on susceptibility to some diseases. Objective: The purpose of this case-control study was to evaluate the association of ABO and Rh blood groups with vitiligo. Patients and Methods: This study was performed on...

An individuals blood group today, is as important as the national identity card. The obvious reason being blood transfusion in cases of emergency. Blood group data of a population is also important from a laboratory viewpoint, since it guides blood banks on number and types of blood to be stored for transfusion services. ABO group data is well established in Pakistan, however A sub-group data i...

BACKGROUND An association between the ABO groups and pancreatic cancer has been shown previously, group A being significantly commoner in affected patients. We conducted the present study to investigate the prognostic effect of ABO blood group on overall survival of pancreas cancer patients. METHODS Patients who were diagnosed between 2005 and 2010 with pancreas cancer at Ankara Numune Educat...

Serological typing for the classical ABO blood groups is routinely performed using anti-A and anti-B antisera of polyclonal or monoclonal origin, which are able to distinguish four phenotypes (A, B, AB, and O). Modern molecular biology methods offer the possibility of direct ABO genotyping without the need for family investigations. Typing can be done with small amounts of DNA and without detec...

BACKGROUND Neonatal jaundice that occurs in ABO or Rhesus issoimunisation has been recognized as one of the major risk factors for development of severe hyperbilirubinemia and bilirubin neurotoxicity. AIM Aim of our study was to investigate clinical and laboratory parameters associated with hemolytic jaundice due to Rh and ABO incompatibility and compare results with the group of unspecific j...

BACKGROUND ABO blood typing in pre-transfusion testing is a major component of the high workload in blood banks that therefore requires automation. We often experienced discrepant results from an automated system, especially weak serum reactions. We evaluated the discrepant results by the reference manual method to confirm ABO blood typing. METHODS In total, 13,113 blood samples were tested w...

BACKGROUND Erythrocyte-magnetized technology (EMT) is a new fully automated method for ABO-RH-K phenotyping and antibody detection. The magnetization of red cells avoids centrifugation and washing phases. This report describes the results of an evaluation of this new technology on its specific automated system. STUDY DESIGN AND METHODS ABO-RH-K phenotyping was compared between EMT and a semia...

BACKGROUND Although the relationship between non-O blood types and the risk of exocrine pancreatic cancer has been demonstrated, the association between ABO blood types and sporadic pancreatic neuroendocrine tumor (PNET) has not been reported thus far. METHODS This hospital-based, case-control study included 387 patients with PNET and 542 age- and sex-matched controls. Unconditional multivari...

In the fall of 2001, the American Board of Orthodontics (ABO) began a committed discussion of early certification after graduation from a recognized orthodontic training program. The board’s intention was 2-fold: to evaluate the possibility of offering early certification to recent graduates by using cases treated during their residencies, by determining whether resident treatment quality could...