Background Regional 20`TI activity after resting injection, imaged early and after redistribution, reflects viable myocardium and can predict improved isotope uptake as well as regional and global ventricular function after revascularization. 9'9Tc-sestamibi, a perfusion tracer with favorable imaging characteristics, has distinct kinetics compared with 20`T1, demonstrating minimal redistributio...

UNLABELLED Preoperative localization of the parathyroids using (99m)Tc-sestamibi scanning has not yet been established as a routine diagnostic procedure for primary hyperparathyroidism. Several studies have demonstrated a variable degree of accuracy (70%-98%) in asymptomatic patients. METHODS We evaluated the accuracy of this technique in 64 patients who underwent scanning between January 200...

The aim of this study was to correlate the uptake of 99mTc-methoxy-isobutyl-isonitrile (MIBI) with ultra-structural features of parathyroid adenomas. Twenty patients with proven primary hyperparathyroidism were evaluated prospectively. Preoperative double-phase 99mTc-MIBI scintigraphy was performed in all patients and the degree of tracer uptake by the parathyroid lesions was assessed visually ...

We report a case of a young Indian male who had an incidental abnormal focal uptake of 99mTechnetium-MIBI (Methoxy Isobutyl Isonitrile) in the right lobe of thyroid while undergoing 99mTc-MIBI myocardial perfusion gated SPECT (Single Photon Emission Computed Tomography) imaging as a part of his myocardial ischemia status evaluation. This focal uptake was eventually detected to be a malignant th...

BACKGROUND Gated single photon emission CT (SPECT) sestamibi imaging allows the simultaneous assessment of myocardial perfusion and left ventricular function. OBJECTIVE The purpose of this study was to evaluate a technique for quantitative regional wall motion assessment using gated SPECT (99m)Tc-sestamibi imaging. PATIENTS AND INTERVENTIONS Fourteen subjects without cardiac pathology and 2...