In the course of molecular studies on Japanese glucose-6-phosphate dehydrogenase (G6PD) variants using single-strand conformation polymorphisms (SSCP) analysis, we found an unusual class 1 G6PD variant that had nucleotide deletion in exon 9. The patient showed chronic nonspherocytic hemolytic anemia associated with frequent episodes of severe hemolytic attack. The hemolysate exhibited no measur...

In two studies, we investigated how bitter taste preferences might be associated with antisocial personality traits. Two US American community samples (total N = 953; mean age = 35.65 years; 48% females) self-reported their taste preferences using two complementary preference measures and answered a number of personality questionnaires assessing Machiavellianism, psychopathy, narcissism, everyd...

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We used record linkage to create a data repository of health information of persons who were federally incarcerated in Ontario and Canada. We obtained records from 56,867 adults who were federally incarcerated between January 1, 1998 and December 31, 2011 from the Correctional Service of Canada; 15,248 records belonged to individuals residing in Ontario, Canada. We linked these records to the R...

Morgan, Kathleen G., and Samudra S. Gangopadhyay. Invited Review: Cross-bridge regulation by thin filament-associated proteins. J Appl Physiol 91: 953–962, 2001.—This minireview will cover current concepts on the identity and mechanistic function of smooth muscle actin binding proteins that may regulate actin-myosin interactions. The potential roles of tropomyosin, caldesmon, calponin, and SM22...

In this work, we introduced a corpus for categorizing edit types in Wikipedia. This fine-grained taxonomy of edit types enables us to differentiate editing actions and find editor roles in Wikipedia based on their low-level edit types. To do this, we first created an annotated corpus based on 1,996 edits obtained from 953 article revisions and built machine-learning models to automatically iden...

OBJECTIVE To prove the existence of a correlation between central corneal thickness and diabetes. METHODS Ultrasound pachymetry measurements were made in 1,000 patients. The sample was divided into two groups of patients: 953 of them were non-diabetic patients, and 47 were diabetic patients. RESULTS The average central corneal thickness in diabetic patients was 571.96 +/- 26.81 microns with...

An analytical expression is found for the accurate ab initio potential energy curve of the fluorine molecule that has been determined in the preceding two papers. With it, the vibrational and rotational energy levels of F(2) are calculated using the discrete variable representation. The comparison of this theoretical spectrum with the experimental spectrum, which had been measured earlier using...

A series of experiments was made to determine the capacity of an archaeal strain, Methanocaldococcus jannaschii to bind metals and to study the effects of metal-binding on the subsequent silicification of the microorganisms. The results showed that M. jannaschii can rapidly bind several metal cations (Fe 3+ , Ca 2+ , Pb 2+ , Zn 2+ , Cu 2+ ). Considering the lack of silicification of this strain...