For patients (pts) with la/mUC, systemic therapy (ST), including chemotherapy and immunotherapy, offers benefits such as improved overall survival (OS). There is no published systematic literature review (SLR) reporting on recent treatment patterns reasons for potential undertreatment in la/mUC. We aimed to comprehensively characterize rates of ST (NST) associated this population. conducted a C...

OBJECTIVE Develop a method for the evaluation of patients nutritional status through a score that expresses universal nutritional status, as well as investigate if that score would be efficient for the prognostic stratification of advanced heart failure (HF) pts. METHODS The score was reached by the selection of evaluation methods that would quantify nutritional status: ideal body weight perc...

Predictors for operative mortality (OM) were studied in 172 consecutive patients (pts) undergoing coronary artery grafts (CAG) for angina pectoris.Seventy eight pts had Class IV angina; of the 147 patients given propranolol, 41 were gradually withdrawn from propranolol and finally discontinued 24 hours before surgery, and 106 were abruptly withdrawn from propranolol 24 hours before CAG; 20 pts ...

BACKGROUND Microalbuminuria has been described as a risk factor for progressive cardiovascular and renal diseases. Little is known about its prognostic value in patients (pts) with established heart failure (HF). OBJECTIVE To assess the role of microalbuminuria as a prognostic marker in patients with chronic HF receiving standard medication. METHODS From January 2008 through September 2009,...

OBJECTIVES Anatomical and functional results of a modified sacral perineocolporectopexy for extreme forms of complex pelvic organs prolapse. MATERIAL AND METHODS Between 2005 and 2010, 10 women aged 47-75 years were treated by abdomino-perineal implantation of polypropylene mesh for modified sacral perineocolporectopexy and subsequently followed-up. They were suffering from enterocele (9 pts)...

OBJECTIVE The aims of this systematic review were to integrate the research on posttraumatic stress (PTS) and posttraumatic stress disorder (PTSD) after termination of pregnancy (TOP), miscarriage, perinatal death, stillbirth, neonatal death, and failed in vitro fertilisation (IVF). METHODS Electronic databases (AMED, British Nursing Index, CINAHL, MEDLINE, SPORTDiscus, PsycINFO, PubMEd, Scie...

RATIONALE Volatile anesthetics inhibit mucociliary clearance in the airways. The two-pore domain K+ channel, TASK-1, represents one of their molecular targets in that they increase its open probability. Here, we determine whether particle transport speed (PTS) at the mucosal surface of the mouse trachea, an important factor of the cilia-driven mechanism in mucociliary clearance, is regulated by...

background: the aim of this study is to evaluate the geometry of the distal femur and the proximal tibia in the osteoarthritic knee using 3d reconstructive ct scan imaging. methods: 449 patients with knee osteoarthritis were treated surgically in our center with patient-specific technology total knee arthroplasty. preoperatively, all the patients underwent a ct scan according to a standard prot...

Emir Salih Magden1*, Purnawirman1, Nanxi Li1, Gurpreet Singh1, Jonathan D. B. Bradley1, Gale S. Petrich1, Gerald Leake2, Douglas D. Coolbaugh2, Michael R. Watts1, Leslie A. Kolodziejski1 Research Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA College of Nanoscale Science and Engineering, University at Albany, 1400 Washington Ave...

Two in vitro and one in vivo experiments were conducted to investigate the effects of a selection of plant compounds on rumen fermentation, microbial concentration and methane emissions in goats. Treatments were: control (no additive), carvacrol (CAR), cinnamaldehyde (CIN), eugenol (EUG), propyl propane thiosulfinate (PTS), propyl propane thiosulfonate (PTSO), diallyl disulfide (DDS), a mixture...