In September 2000, two instances of life-threatening hepatotoxicity were reported in health-care workers taking nevirapine (NVP) for postexposure prophylaxis (PEP) after occupational human immunodeficiency virus (HIV) exposure. In one case, a 43-year-old female health-care worker required liver transplantation after developing fulminant hepatitis and end-stage hepatic failure while taking NVP, ...

Objectives: After reading this continuing education article, the pharmacist should be able to do the following: 1. Discuss the various etiologies of Parkinson’s disease. 2. Describe the major signs and symptoms associated with the disease. 3. Outline a rational therapeutic approach for the treatment of Parkinson’s disease. 4. Name the principal drugs and chemicals that may cause symptoms of the...

BACKGROUND A recent estimate by the World Health Organization (WHO) suggests that 161 million persons worldwide have visual impairment, including 37 million blind (best-corrected visual acuity less than 3/60 in the better eye) and 124 million with visual impairment less severe than blindness (best-corrected acuity less than 6/18 to 3/60 in the better eye). This estimate is quoted widely, but be...