نتایج جستجو برای: 543 55029 rostango

تعداد نتایج: 2371  

Journal: :The Lancet. Infectious diseases 2014
David M Wagner Jennifer Klunk Michaela Harbeck Alison Devault Nicholas Waglechner Jason W Sahl Jacob Enk Dawn N Birdsell Melanie Kuch Candice Lumibao Debi Poinar Talima Pearson Mathieu Fourment Brian Golding Julia M Riehm David J D Earn Sharon Dewitte Jean-Marie Rouillard Gisela Grupe Ingrid Wiechmann James B Bliska Paul S Keim Holger C Scholz Edward C Holmes Hendrik Poinar

BACKGROUND Yersinia pestis has caused at least three human plague pandemics. The second (Black Death, 14-17th centuries) and third (19-20th centuries) have been genetically characterised, but there is only a limited understanding of the first pandemic, the Plague of Justinian (6-8th centuries). To address this gap, we sequenced and analysed draft genomes of Y pestis obtained from two individual...

Journal: :Molecular cancer research : MCR 2006
Laura E MacConaill Christina M Hughes Orit Rozenblatt-Rosen Suraj Nannepaga Matthew Meyerson

Multiple endocrine neoplasia type 1 (MEN-1) is a heritable syndrome typified by tumors in multiple endocrine organs, including the pituitary, parathyroids, and pancreatic islets. MEN-1 is attributable to mutations in the MEN1 tumor-suppressor gene that encodes the menin protein. Recent studies have implicated menin in transcriptional regulation and in covalent histone modification; however, lit...

2015
Li-Bo Yang Lin-Yong Sun Yong Jiang Ying Tang Zhi-Hui Li Hong-Ying Zhang Hong Bu Feng Ye

The BRAF(V600E) mutation is commonly found in papillary thyroid cancers (PTCs) at different frequencies in different regions. However, the association between the BRAF(V600E) mutation and clinicopathological features in Chinese PTC patients is unknown. A total of 543 Chinese patients with histologically confirmed PTC were enrolled in this study. For the BRAF mutation assay, the target fragments...

2017
Antonio MacKenna Javier Crosby Cristián Huidobro Eduardo Correa Gonzalo Duque

OBJECTIVE The main objective of this study was to assess semen characteristics of patients with testicular cancer before cryopreservation and after thawing, to evaluate the consequences of this technique on sperm quality in patients with testicular cancer. METHODS Five hundred eighty-nine samples from 543 patients with testicular cancer were cryopreserved between 1995 and 2015, one aliquot pe...

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