Abstract Introduction Acquired buried penis is a common condition in obese patients. Abnormal excess fat accumulation under the pubic skin leads to partially or completely disappearance of penis. This related voiding difficulties and sexual dysfunction. The goal surgical treatment expose full penile lengthy by excising adipose tissue part skin. Objective aim this kind surgery make possible have...

Sebum provides vital cutaneous functions including moisture retention and defense against the external environment, pathogens. Despite well-defined homeostatic of sebum in fortifying skin barrier, role microbiota-immune system axis regulation remains unclear. We have recently shown that keratinocyte-derived cytokine thymic stromal lymphopoietin (TSLP) promotes secretion through T cell stimulati...

Achievement of critical dimensions after wholesale removal of stock from large, ring rolled Waspaloy forgings and fabrications has been complicated by residual stresses induced via rapid quench from the solution heat treat cycle. Part movement during machining can be reduced significantly by substituting air cool for the oil quench commonly specified to achieve high mechanical strengths. Howeve...

Typical assays used to discover and analyze small molecules that inhibit the hepatitis C virus (HCV) NS3 helicase yield few hits and are often confounded by compound interference. Oligonucleotide binding assays are examined here as an alternative. After comparing fluorescence polarization (FP), homogeneous time-resolved fluorescence (HTRF®; Cisbio) and AlphaScreen® (Perkin Elmer) assays, an FP-...

PURPOSE Inflammatory breast cancer (IBC) is a rare but particularly aggressive form of primary breast cancer. The molecular mechanisms responsible for IBC are largely unknown. EXPERIMENTAL DESIGN To obtain further insight into the molecular pathogenesis of IBC, we used real-time quantitative reverse transcription (RT)-PCR to quantify the mRNA expression of 538 selected genes in IBC relative t...