.............................................................................................................................. 2 TABLE OF CONTENTS ........................................................................................................... 3 INTRODUCTION ...................................................................................................................... 5 1.1 Pr...

We investigated systematically the effects of Tet-induced oxidation products of 5-methylcytosine on Dnmt1- and DNMT3a-mediated cytosine methylation in synthetic duplex DNA. We found that the replacement of 5-methylcytosine at a CpG site with a 5-hydroxymethylcytosine, 5-formylcytosine, 5-carboxylcytosine or 5-hydroxymethyluracil resulted in altered methylation of cytosine at both the opposite a...

in current century, success of organizations is dependent on the correct management of knowledge and also knowledge management (km) successful implementation relies on its critical success factors (csfs). identifying these critical factors can help businesses in planning and implementing knowledge management. hence, this study aims to propose a conceptual model with the csfs approach in order t...

many of injured children will require surgical treatment with involvement of the anesthesiologist. the anesthesia providers may have to take care of pediatric patients on following occasions: 1- initial stabilization in the emergency department 2- providing sedation and monitoring for imaging 3- preoperative management of emergent surgical procedures such as laparotomy or craniotomy 4- manageme...

Many of injured children will require surgical treatment with involvement of the anesthesiologist. The anesthesia providers may have to take care of pediatric patients on following occasions: 1- Initial stabilization in the emergency department 2- Providing sedation and monitoring for imaging 3- Preoperative management of emergent surgical procedures such as laparotomy or craniotomy 4- Manageme...