نتایج جستجو برای: 5 fluorouracil

تعداد نتایج: 1220120  

2013
Kavitha K Srinivasa Rao

Article history: Received on: 11/01/2013 Revised on: 29/01/2013 Accepted on: 15/01/2013 Available online: 30/03/2013 The drug 5 fluorouracil is sparingly soluble in water. The aqueous solubility and dissolution rate of 5-fluorouracil can be increased by inclusion complexation with β-cyclodextrin. Molecular-modeling studies support the formation of stable molecular inclusion complexation of 5-fl...

Journal: :The journal of physical chemistry. A 2005
Nadezhda Markova Venelin Enchev Iliana Timtcheva

Post-Hartree-Fock ab initio quantum chemical calculations were performed for 5-fluorouracil in the gas phase and in a three-water cluster. Full geometry optimizations of the 5-fluorouracil-water complexes were carried out at the MP2/6-31+G(d,p) level of theory. MP4/6-31+G(d,p)//MP2/6-31+G(d,p) and MP4/6-31++G(d,p)//MP2/6-31+G(d,p) single-point calculations were performed to obtain more accurate...

Journal: :The Journal of bone and joint surgery. American volume 2009
Chunfeng Zhao Mark E Zobitz Yu-Long Sun Kelly S Predmore Peter C Amadio Kai-Nan An Steven L Moran

BACKGROUND Topical 5-fluorouracil has been reported to reduce adhesions in animal models of tenolysis. The purpose of this study was to investigate the effects of topical 5-fluorouracil on adhesion formation after tendon repairs were subjected to immediate postoperative rehabilitation in a canine model in vivo. METHODS Sixty dogs were randomly assigned to either a 5-fluorouracil treatment (th...

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