Kadambi, Vivek J., Nancy Ball, Evangelia G. Kranias, Richard A. Walsh, and Brian D. Hoit. Modulation of force-frequency relation by phospholamban in genetically engineered mice. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H2245–H2250, 1999.—Phospholamban levels regulate cardiac sarcoplasmic reticulum Ca21 pump activity and myocardial contractility. To determine whether and to what extent pho...

Kim, Eun-Mee, Martha K. Grace, Catherine C. Welch, Charles J. Billington, and Allen S. Levine. STZ-induced diabetes decreases and insulin normalizes POMC mRNA in arcuate nucleus and pituitary in rats. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1320–R1326, 1999.—Effects of streptozotocin (STZ)-induced diabetes and insulin on opioid peptide gene expression were examined in r...

Peng, Y., O. W. Moe, T.-S. Chu, P. A. Preisig, M. Yanagisawa, and R. J. Alpern. ETB receptor activation leads to activation and phosphorylation of NHE3. Am. J. Physiol. 276 (Cell Physiol. 45): C938–C945, 1999.—In OKP cells expressing ETB endothelin receptors, activation of Na1/H1 antiporter activity by endothelin-1 (ET-1) was resistant to low concentrations of ethylisopropyl amiloride, indicati...

MICHAEL S. EXTON,1 MARC SCHULT,2 STEFAN DONATH,3 TIM STRUBEL,3 ULRIKE BODE,3 ADRIANA DEL REY,4 JÜRGEN WESTERMANN,3 AND MANFRED SCHEDLOWSKI1 1Institute for Medical Psychology, Faculty of Medicine, University of Essen, 45122 Essen; Divisions of 2Abdominal and Transplantation Surgery and 3Functional and Applied Anatomy, Hannover Medical School, 30623 Hannover; and 4Institute of Physiology, Divisio...

Kleine, Teri J., Gerald J. Gleich, and Simon A. Lewis. Eosinophil peroxidase increases membrane permeability in mammalian urinary bladder epithelium. Am. J. Physiol. 276 (Cell Physiol. 45): C638–C647, 1999.—Eosinophil peroxidase (EPO), a cationic protein found in eosinophils, has been reported to be cytotoxic independent of its peroxidase activity. This study investigated with electrophysiologi...

MARK O. BEVENSEE,1 ESTHER BASHI,1 WOLF-RÜDIGER SCHLUE,2 GREGORY BOYARSKY,3 AND WALTER F. BORON1 1Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520; 2Institut für Neurobiologie, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany; and 3Department of Physiology and Biophysics, University of Texas Medical Branch, Galvesto...

This study was undertaken to elucidate the effect of diallyl disulfide from Allium sativum, an oil-soluble organosulfur compound found in garlic, in suppressing human non-small cell lung carcinoma H1299 cells. A potent increase in apoptotic cells has accompanied 1) a decrease in cell viability, 2) an increase of the fraction of G2/M-phase cells by up to 48.80 %, and 3) a transient increase of t...

Doolen, Suzanne, Diana N. Krause, and Sue P. Duckles. Estradiol modulates vascular response to melatonin in rat caudal artery. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1281–H1288, 1999.—The purpose of this study was to determine whether estrogen modulates the function of vascular melatonin receptors. We used the rat caudal artery and found that the contractile effects of melatonin were i...

A 19-year-old male college basketball player experienced onset of pain after playing 4 games in 2 days. Clinical examination revealed mild swelling over the mid-left tibia. There were no signs of infection. We obtained radiographs (Fig. 1). The radiological differential diagnosis at this stage included focal cortical abscess related to infection, stress fracture and osteoid osteoma. Computed to...

Foreman, R. D., R. W. Blair, H. R. Holmes, and J. A. Armour. Correlation of ventricular mechanosensory neurite activity with myocardial sensory field deformation. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R979–R989, 1999.—The mechanosensory activity generated by ventricular epicardial sensory neurites associated with afferent axons in thoracic sympathetic nerves was correl...