نتایج جستجو برای: 4 triazole derivatives
تعداد نتایج: 1393281 فیلتر نتایج به سال:
The triazole nucleus is an important part of the therapeutically interesting drug candidate as antimicrobial, analgesic, anticancer, anticonvulsant and anti-inflammatory agents. Therefore, a number of 1,2,3& 1,2,4-triazole derivatives were synthesized. The structures of these compounds were characterized by means of FT-IR, H-NMR, and elemental analysis. All the compounds were evaluated for anti...
Small-molecule ligands that bind to misfolded protein aggregates are essential tools for the study and detection of pathological hallmarks in neurodegenerative disorders, such as Alzheimer’s disease (AD). In the present study, three compounds (one benzothiazole-triazole, L1, and two benzothiadiazoletriazoles, L2 and L3) were synthesized via a modular approach (azide–alkyne cycloaddition) and ev...
Ligands incorporating a tetraazamacrocycle receptor, a 'click'-derived triazole and a 1,8-naphthalimide fluorophore have proven utility as probes for metal ions. Three new cyclam-based molecular probes are reported, in which a piperidinyl group has been introduced at the 4-position of the naphthalimide fluorophore. These compounds have been synthesized using the copper(I)-catalyzed azide-alkyne...
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