نتایج جستجو برای: 4 hydroxy 2 nonenal

تعداد نتایج: 3126698  

Journal: :Acta Crystallographica Section E Structure Reports Online 2012

2013
Ichiya Sano Sachiko Kaidzu Masaki Tanito Katsunori Hara Tsutomu Okuno Akihiro Ohira

Oxidative stress has been suspected of contributing to the pathogenesis of pterygia. We evaluated the immunohistochemical localization of the markers of oxidative stress, that is, the proteins modified by 4-hydroxyhexenal (4-HHE) and 4-hydroxynonenal (4-HNE), which are reactive aldehydes derived from nonenzymatic oxidation of n-3 and n-6 polyunsaturated fatty acids, respectively. In the pterygi...

Journal: :Chemico-biological interactions 2010
Nicolas J Pillon Laurent Soulère Roxane E Vella Marine Croze Bertrand R Caré Hedi A Soula Alain Doutheau Michel Lagarde Christophe O Soulage

Lipid peroxidation is one of the most important sources of endogenous toxic metabolites. 4-Hydroxy-2-nonenal (HNE) and 4-hydroxy-2-hexenal (HHE) are produced in several oxidative stress associated diseases from peroxidation of n-6 and n-3 polyunsaturated fatty acids, respectively. Both are able to form covalent adducts with many biomolecules. Particularly, proteins adduction can induce structur...

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