The environmental effects of 4,4’-methylenediphenyl diisocyanate (MDI) are linked with its potential hydrolytic conversion to 4,4’-methylenedianiline (MDA). Likewise, the reactions MDI biological macromolecules govern absorption, distribution, metabolism, and excretion processes associated sensitization toxicological effects, formation MDA in body would be a source additional concern. To obtain...

Antihistamines are effective for treatment of seasonal nasal allergy. Recently, prophylactic treatment with antihistamines in patients with pollinosis was reported to be more effective when started before the pollen season. The administration with antihistamines from 2 to 6 weeks before onset of the pollen season is recommended for management of allergic rhinitis in Japan. To determine the reas...

Abstract Soy flour can be substituted in polymeric diphenylmethane diisocyanate (pMDI) resin for bonding plywood. Resin bleed-through is avoided by prepressing at 95°C. The boards have greater wet and dry strength than do those prepared from melamine-urea-formaldehyde (MUF) resin. also emulsion polymer isocyanates cold-press applications. soy increases but keeps the unchanged. optimal level of ...

Toluene diisocyanate (TDI) is the most common cause of occupational asthma in western countries. The aim of this study was to investigate whether genetic factors are involved in toluene diisocyanate-induced asthma. We studied the frequency of human leucocyte antigen (HLA) class II genetic markers in three groups of subjects: 1) subjects with TDI-induced asthma (n = 30); 2) exposed subjects with...

An improved method was developed and validated for measuring low-level concentrations of toluene diisocyanates (TDls) in air. The method is based on OSHA Method 42 for industrial applications. Airborne TDls were trapped on a 25-mm glass-fiber filter impregnated with 50 pg of 1-(2pyridy1)piperazine. A filter holder for was constructed to minimize contamination and losses of the analytes. The der...