نتایج جستجو برای: 375
تعداد نتایج: 6827 فیلتر نتایج به سال:
OBJECTIVES Rituximab is effective in inducing remission in ANCA-associated vasculitis (AAV), with randomized evidence to support its use as four infusions of 375 mg/m(2) (the conventional lymphoma dosing schedule). As B cell depletion (BCD) appears to occur very rapidly after the first dose, we questioned the need for repeat dosing and adopted a standard single-dose protocol of 375 mg/m(2) to t...
OBJECTIVE We previously performed a meta-analysis of microRNA profiling studies on head and neck/oral cancer (HNOC), and identified 11 consistently dysregulated microRNAs in HNOC. Here, we evaluate the diagnostic values of these microRNAs in oral tongue squamous cell carcinoma (OTSCC) using oral cytology samples. MATERIALS AND METHODS The levels of 11 microRNAs were assessed in 39 oral cytolo...
BACKGROUND AND PURPOSE Neurocognitive dysfunction complicates coronary artery bypass surgery. Erythropoietin may be neuroprotective. We sought to determine whether human recombinant erythropoietin would reduce the incidence of neurocognitive dysfunction after surgery. METHODS We randomly assigned 32 elective first-time coronary artery bypass graft patients to receive placebo or 375 U/kg, 750 ...
AIMS Circulating microRNAs (miRNAs) may represent a novel class of biomarkers; therefore, we examined whether acute myocardial infarction (MI) modulates miRNAs plasma levels in humans and mice. METHODS AND RESULTS Healthy donors (n = 17) and patients (n = 33) with acute ST-segment elevation MI (STEMI) were evaluated. In one cohort (n = 25), the first plasma sample was obtained 517 ± 309 min a...
OBJECTIVES The genetic barrier (defined as the number of genetic transitions/transversions needed to produce a resistance mutation) can differ between HIV-1 subtypes. The genetic barrier for the new attachment inhibitor BMS-626529 was evaluated in five HIV-1 subtypes. METHODS Nine substitutions associated with BMS-626529 resistance at seven amino acid positions (116, 204, 375, 426, 434, 475 a...
Backgrounds and Objective: Titanium dioxide (TiO2) is a potent photosensitizer in photodynamic therapy (PDT) and is activated upon ultraviolet (UV) irradiation.The aim of this study was the assessment of the effect of nitrogen –nano doped of titanium dioxide in human A-375 melanoma cancer cell line. Materials and Methods: N-TiO2 nanoparticles were prepared by mechanical mixing of urea with T...
امروزه علف کش ها یکی از نهاده های مهم و ضروری در نظام های کشاورزی پیشرفته محسوب می شوند به علت اینکه هیچگونه علفکش پیش رویشی و پس رویشی در زراعت آفتابگردان به خاطر ترس از خسارت به محصول و عدم کنترل مناسب علفهای هرز، به طور رسمی به کار نرفته است. لذا بدین منظور، آزمایشی در سال زراعی 1387 در مزرعه تحقیقاتی دانشکده کشاورزی دانشگاه بیرجند واقع در عرض جغرافیایی 56َ و ?32 و ارتفاع 1480متر از سطح دریا،...
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