Background: Phytoestrogens are some plant compounds with estrogenic biological effects which are found in many nutritional sources as soybean, flaxseed, and sesame. Vitex agnus-castus, also called Vitex, owns  phytoestrogen properties. Studies have shown that phytoestrogens have different impacts on the gestation process and reproduction indices. Objective: The present study was aimed to inves...

OBJECTIVE To describe the use of symptom-relieving drugs (antimuscarinic drugs or duloxetine) before and after surgery for urinary incontinence (UI); and for those with use of antimuscarinic drugs or duloxetine before surgery, to estimate the risk of being a postoperative user, relative to those without use before surgery. DESIGN A historical population-based cohort study. SETTING Denmark. ...

This study aimed to investigate the effects of statin use on incidence brain tumors. The Korean National Health Insurance Service—National Sample Cohort from 2005 2019 was used. 1893 patients who were diagnosed with tumors matched 7572 control for demographic variables. history dyslipidemia collected, and their prescription statins before diagnosis tumor examined. participants without set as a ...

Introduction: PCOS is an important reproductive and endocrine disorder in women in the reproductive age. Present reports indicate that Vitex agnus-castus acts through hypothalamus-pituitary axis. This study was carried out to evaluate the effects of Vitex fruit hydroalcoholic extract on the alteration of sex hormones in a PCOS animal model. Methods: Following 14 days of monitoring of estrous...

Abstract Background Mirikizumab [(miri), a p19-directed IL-23 antibody] has been shown to be effective in patients with moderately severely active ulcerative colitis (UC) Phase 3, randomised, double-blind, placebo-controlled trials (LUCENT-1 NCT03518086; LUCENT-2 NCT03524092).1 Given the importance of understanding treat-to-target strategies, relationship between improved histologic and endosco...

Chapter 10 Micronutrients II: Trace Elements ...............................................................................357 Individual trace elements. ................................................................................................................362 Zinc ............................................................................................................................