In the present work, we have synthesized thiazole-hydrazone conjugates 5(a–h) and characterized them using various analytical techniques such as UV, IR, NMR, mass spectrometry. Solvatochromic properties were evaluated in ten solvents with different polarity quantum chemical parameters a DFT study. The antibacterial activity results revealed that compounds 5c, 5d 5g exhibited good efficacy remai...

heterogeneous reagent systems have many advantages such as simple experimental procedures, mild reaction conditions and minimization of chemical wastes as compared to the liquid phase counterparts. al(hso4)3 as an heterogeneous, efficient, readily available, and cheap catalyst was synthesized and applied for the synthesis of 1,3-benzo[d]thiazole derivatives by condensation protocol of 2-aminoth...

Simple three-component reactions between dialkyl acetylenedicarboxylate, primary amines and isothiocyanates in the presence of catalytic amount of ZnO nanorods are investigated in water at room temperature which produced thiazole derivatives in good yields.