نتایج جستجو برای: 3 ige سرم
تعداد نتایج: 1830619 فیلتر نتایج به سال:
human basophils play a key role in allergic diseases such as asthma and in a variety of immunological disorders. the generation of il-4 and il-13 can be induced from basophil by ige-mediated and non-ige-mediated mechanisms. time and stimulus- dependent differences in the regulation of these cytokines could have relevance to their biological effects. the aim o...
the presence of immune factors in inflamed dental pulps, suggests that immune responses could participate in disease process. with regard to the presence of significant number of mast cells in pulpitis cases, the purpose of this study was to determine the correlation between concentration and presence of ige in supernatant fluids of explants cultures of different states of dental pulps. for thi...
BACKGROUND Sensitization in early childhood may precede respiratory allergy in adolescence. METHODS IgE reactivity against 132 allergen molecules was evaluated using the MeDALL microarray in sera obtained from a random sample of 786 children at the age of 4, 8 and 16years in a population based birth cohort (BAMSE). Symptoms were analyzed by questionnaire at ages 4, 8 and 16years. Clinically a...
Objective. To study predictors of bronchial asthma development in children 3-4 years old with recurrent broncho-obstructive syndrome by 5-6 age. Material and methods. The authors conducted a prospective cohort 2018-2020 the participation 61 aged 3–4 syndrome. Inclusion criteria: age years; ? 3 episodes past 12 months; informed voluntary consent. At first visit scientists determined levels serum...
Atopic dermatitis (AD) has become a serious epidemic in Korean children. We aimed to investigate the association between vitamin C, E and other nutrients, and serum total IgE/specific IgE levels in children with AD. A total of 119 children (0-24 mo) diagnosed with AD were recruited for this cross-sectional study from a medical center in Seoul. A 24 h recall was used to assess dietary intakes. S...
Two types of receptors for the Fc portion of human IgE (FccR) have been identified on the surface of human cells. These two types of receptors differ in their affinity for IgE as well as in their cellular distribution and function (1) . Type 1 FcER (FcERI) show high affinity (109/M) for IgE and are detectable on mast cells and basophils (2) . The reaction between allergens and IgE bound to FCER...
It is important to know which individuals in the general population have increased susceptibility to air pollution. The aim of this study was to identify susceptible subgroups by studying airways hyperresponsiveness (AHR), high total immunoglobulin (Ig)E and sex. Diary data on lower and upper respiratory symptoms (LRS and URS, respectively), cough, and morning and evening peak expiratory flow (...
We studied the role of IL-4 in human IgE formation in severe combined immunodeficient mice engrafted with peripheral blood mononuclear leukocytes (hu-PBL-SCID). PBL from four nonatopic donors produced only small (< 20 ng/ml) or undetectable amounts of IgE in SCID mice whereas engrafted PBL from seven atopic donors secreted IgE with IgE serum levels reaching a mean +/- SE of 184 +/- 37 ng/ml (n ...
CONTEXT The diagnostic algorithm for human allergic disease involves confirmation of sensitization by detection of allergen-specific immunoglobulin E (IgE) antibody in individuals suspected of having allergic disease because of a history of allergic symptoms after known allergen exposure. Previous studies showed wide disparity among clinically reported allergen-specific IgE levels from differen...
BACKGROUND Immunoglobulin E (IgE) binds to high affinity receptor FcεRI numerously expressed on mast cells. Recent findings have revealed that IgE by itself may regulate various aspects of mast cell biology, however, detailed data is still limited. METHODOLOGY/FINDINGS Here, we have examined the influence of IgE alone, used at different concentrations, on mast cell activity and releasability....
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