The purpose of this study was to determine the role of lipotoxicity in vascular smooth muscle (VSM). C(1)-BODIPY 500/510 C(12) used to assess the ability of VSM A7r5 cells to transport long-chain fatty acids showed that lipid transport did not appear to limit metabolism. Thin layer chromatography revealed that storage of transported fatty acid occurred primarily as mono- and diglycerides and fa...

The effect of various fatty acids on lipid peroxidation of liver microsomes induced by different methods in vitro was studied using oxygen uptake and malonaldehyde (MDA) production. It was observed that fatty acids with a single double bond are effective inhibitors of peroxidation. Stereo and positional isomers of oleic acid were equally effective as oleic acid. There was an absolute requiremen...

background and purpose: recent reports suggest that increased homocysteine is a risk factor for heart disease. on the other hand, regular exercise and supplementation of omega-3 fatty acids have been effective in reducing these diseases. the purpose of this study was to evaluate the interaction effect of 8 weeks of aerobic training and omega-3 fatty acid supplementation on plasma homocysteine c...

Drought affects yield of peanut, but its effect on oleic and linoleic acids that influence its oil quality of peanut genotypes with different levels of drought resistance has not been clearly investigated. Therefore, the aims of this research were to determine whether soil water levels could affect oil quality by changes in fatty acid compositions of peanut, and to investigate the changes i...

The role played by membrane lipid environment on cardiac function remains poorly defined. The polyunsaturated fatty acid profile of myocardial phospholipids could be of utmost importance in the regulation of key-enzyme activities. This study was undertaken to determine whether selective incorporation of n-6 or n-3 fatty acids in membrane phospholipids might influence cardiac mechanical performa...

polyunsaturated fatty acids (pufas) particularly ω-3 pufas showed great assure in prevention of cardiovascular diseases (cvd). the evidence for cv benefits of pufa comes from eicosapentaenoic acid (epa) with or without docosahexaenoic acid (dha) in primary prevention, after myocardial infarction (mi), with heart failure (hf). the epidemiologic studies and trials showing the benefits of pufa, sp...

ôbjective: ït has been shown that serum and red blood cells’ level of ômega-3 fatty acids are low in people with schizophrenia. many studies have, therefore, attempted to explore the beneficial effects of these substances in the management of schizophrenia. however, the outcomes of the previous studies have not been clear cut. the present study is an attempt to retest this hypothesis by elimina...

objective(s): occludin is essential for proper assembly of tight junctions (tjs) which regulate paracellular endothelial permeability. omega-3 polyunsaturated fatty acids (ω-3 pufa) protect endothelial barrier function against injury. materials and methods: we examined anti-inflammatory effect of ω-3 pufa intake (30 mg/kg/day for 10 days) on expression and location of occludin in the aorta of a...

in this study, the effects of incorporating grape seed powder (gsp) on flour physicochemical properties i.e. particle size, crude protein, fiber, wet gluten and gluten quality (zeleny test), and dough rheological properties were investigated. increasing incorporation levels of gsp from 5 to 25% (w/w flour basis) led to an increase in the amount of fat, total phenol, and total dietary fiber; whe...