Song and colleagues deliver a thorough and fair review of the initial clinical investigations of a new paradigm in radiotherapy most recently called stereotactic body radiation therapy (SBRT).[1] Oncology observers may take exception with the use of the designation “new paradigm.” After all, from a tumor control point of view, skeptics might say, “radiotherapy is radiotherapy.” Recent advances ...

In frames of dS/CFT correspondence suggested by Strominger we calculate holographic conformal anomaly for dual euclidean CFT. The holographic renormalization group method is used for this purpose. It is explicitly demonstrated that two-dimensional and four-dimensional conformal anomalies (or corresponding central charges) have the same form as those obtained in AdS/CFT duality. [email protected]...

Background and Purpose: Despite the progress in treatment modalities such as neurosurgery and radiotherapy, almost all patients treated with malignant gliomas develop recurrent tumors and die of their disease. The aim of this study was to determine response, survival and treatment toxicities after reirradiation of relapsing primary malignant brain gliomas. Material and Methods: Twenty patients ...

We study four-dimensional superconformal field theories coupled to three-dimensional superconformal boundary or defect degrees of freedom. Starting with bulk N = 2, d = 4 theories, we construct abelian models preserving N = 2, d = 3 supersymmetry and the conformal symmetries under which the boundary/defect is invariant. We write the action, including the bulk terms, in N = 2, d = 3 superspace. ...

Objective: The purpose of this dosimetric study is the targeted dose homogeneity and critical organ dose comparison of 7-field Intensity Modulated Radiotherapy (IMRT) and 3-D 4-field conformal radiotherapy. Study Design: Cross sectional study. Material and Methods: Twenty patients with low and moderate risk prostate cancer treated at Gülhane Military Medical School Radiation Oncology Department...

PURPOSE We compared dosimetry and clinical toxicity for 3-dimensional conformal radiotherapy (3D-crt), intensity-modulated radiotherapy (imrt), and RapidArc (Varian Medical Systems, Palo Alto, CA, U.S.A.) in locally advanced pancreatic cancer (lapcc). We hypothesized that the technique with better sparing of organs at risk (oars) and better target dose distributions could lead to decreased clin...

There is a clear dose response for localized prostate cancer radiotherapy and there probably is a radiobiological rationale for hypo-fractionation. Combining the two should maximize tumor control and increase the therapeutic ratio. This study examines the rationale and technical feasibility of CyberKnife radiotherapy (a robotic arm-driven linear accelerator) for localized prostate cancer. Its a...

PURPOSE Hypofractionated radiotherapy may overcome repopulation in rapidly proliferating tumors such as lung cancer. It is more convenient for the patients and reduces health care costs. This study reports our results on patients with medically inoperable, early stage, non-small cell lung cancer (NSCLC) treated with hypofractionation. MATERIALS AND METHODS Stage T1-2N0 NSCLC patients were tre...